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The effects of three nonsteroidal anti-inflammatory drugs on operative mydriasis maintaining and postoperative inflammation

Poster Details

First Author: T.Sarenac Vulovic SERBIA

Co Author(s):    S. Sreckovic   N. Petrovic   M. Janicijevic Petrovic   K. Janicijevic   D. Todorovic   S. Jovanovic     

Abstract Details

Purpose:

The aim of this study was to compare the effects of tree non-steroidal anti-inflammatory drugs (Indomethacyn, Diclofenac andd Nepavenac) compared to sterod therapy in patients underwent cataracts urgery.

Setting:

Clinic of ophthalmology, Clinical Centre Kragujevac, Kragujevac, Serbia Faculty of Medical sciences, Department of ophthalmology, University of Kragujevac, Serbia

Methods:

Our study included 100 patients referred to cataract surgery, taking into account excluding criteria. All partients were divided in four groupps (n=25): Igroup-pre/postoperative Intomethacyn 0.1%; II group-pre/postoperative Diclofenac 0.1%; III group- pre/postoperative Nepavenac 0.1%; and IV group-postoperative steroid single. During our examination, we measured: intraoperative pupil diameter changes, postoperative anterior chamber inflammation.

Results:

Our results indicated that intraoperative mydriasis maintaing was better in groups with preoperative using of non steroid anti-inflammatory drugs compared with patients with single steroid postoperatively, with statistical significance (p<0.05). There was no statistical significance differences between the groups using non steroidal anti-inflammatory drugs (p>0.05). Also, postoperative inflammation was statistically significant less in patients with pre/postoperatively used non steroid antiinflammatory drugs compared with steroid only postroperatively used patients (p<0.05), measured in appropriate intervals. There was no statistical singnificant differences between the first three examined groups.

Conclusions:

: Non steroidal antiinflammatory drugs used pre/postoperatively can maintain the mydriasis during cataract surgery; and thay reduce postoperatively inflammation in anterior chamber.

Financial Disclosure:

NONE

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