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The effects of three nonsteroidal anti-inflammatory drugs on operative mydriasis maintaining and postoperative inflammation

Poster Details

First Author: T.Sarenac Vulovic SERBIA

Co Author(s):    S. Sreckovic   N. Petrovic   M. Janicijevic Petrovic   K. Janicijevic   D. Todorovic   S. Jovanovic     

Abstract Details


The aim of this study was to compare the effects of tree non-steroidal anti-inflammatory drugs (Indomethacyn, Diclofenac andd Nepavenac) compared to sterod therapy in patients underwent cataracts urgery.


Clinic of ophthalmology, Clinical Centre Kragujevac, Kragujevac, SerbiaFaculty of Medical sciences, Department of ophthalmology, University of Kragujevac, Serbia


Our study included 100 patients referred to cataract surgery, taking into account excluding criteria. All partients were divided in four groupps (n=25): Igroup-pre/postoperative Intomethacyn 0.1%; II group-pre/postoperative Diclofenac 0.1%; III group- pre/postoperative Nepavenac 0.1%; and IV group-postoperative steroid single. During our examination, we measured: intraoperative pupil diameter changes, postoperative anterior chamber inflammation.


Our results indicated that intraoperative mydriasis maintaing was better in groups with preoperative using of non steroid anti-inflammatory drugs compared with patients with single steroid postoperatively, with statistical significance (p<0.05). There was no statistical significance differences between the groups using non steroidal anti-inflammatory drugs (p>0.05). Also, postoperative inflammation was statistically significant less in patients with pre/postoperatively used non steroid antiinflammatory drugs compared with steroid only postroperatively used patients (p<0.05), measured in appropriate intervals. There was no statistical singnificant differences between the first three examined groups.


: Non steroidal antiinflammatory drugs used pre/postoperatively can maintain the mydriasis during cataract surgery; and thay reduce postoperatively inflammation in anterior chamber.

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