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Comparison of central corneal thickness measurement between spectral domain ocular coherence tomography and optical low coherence reflectometry

Poster Details

First Author: D.Sousa PORTUGAL

Co Author(s):    I. Leal   L. Abegao Pinto   C. Marques-Neves              

Abstract Details


To compare the AngioVue�Â�®/RTVue�Â�® spectral optical coherence tomography (SD-OCT) and Lenstar�Â�® optical low coherence reflectometry (OLCR) devices in terms of measuring central corneal thickness (CCT).


Ophthalmology Dept., Hospital de Santa Maria, Lisboa, PT.


Cross-sectional study. Sixty eyes of 30 patients were included. An experienced observer obtained measurements of CCT by using SD-OCT and OLCR. Measurements were performed in the same room, at the same time of the day for each patient. Only images with high-quality acquisition signal were considered. The tenets of the Declaration of Helsinki were followed. A paired t-test was used to compare both measurements. Statistical analyses were performed using STATA 13.1.


Studied population included 30 subjects (14 women), with a mean age of 28.8 �Â�± 4.2 [range 22-37] years and a spherical equivalent of -1.7 �Â�± 1.5 diopters. Mean OLCR right and left eye CCT measurements were 535.9 �Â�± 8.0 �Î�¼m and 538.5 �Â�± 7.9 �Î�¼m, respectively. Mean SD-OCT right and left eye CCT measurements were 518.6 �Â�± 7.7 �Î�¼m and 521.9 �Â�± 7.9 �Î�¼m, respectively. The paired t-test analysis found a statistically significant change between OLCR and SD-OCT measurements for both eyes (p < 0.001).


In our sample, the CCT measurements obtained with OLCR were significantly higher than those obtained with the SD-OCT. The difference between means was higher than 10 �Î�¼m. These results should trigger furthers research, such as repeatability and reproducibility studies, to better elucidate how these differences may affect clinical decisions.

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