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Topography of the demarcation line after UV corneal cross-linking with progressive keratoconus

Poster Details

First Author: E.Usubov RUSSIA

Co Author(s):    M. Bikbov   V. Surkova   L. Khalimova   K. Titoyan   S. Mukhamadieva        

Abstract Details


of the study was to determine the topographic location of the stromal line of demarcation after the standard corneal cross-linking in keratoconus.


Ufa eye research institute


12 patients (15 eyes) with a progressive keratoconus of 1-2 stages by the Amsler-Kruimerich classification underwent the study. The mean age varied from 18 to 46 years, the corneal thickness averaged 468�Â�±25 �Î�¼m, the refractive power of the cornea Kmax - on the average 49,7�Â�±2,6D. All patients underwent the procedure of UV cross-linking according to the standard 'Dresden' protocol with 0.1% aqueous solution of riboflavin


After 2-3 weeks, a slight pseudohaze was in 8 cases (53%). After 1 month, in 13 cases (87%), a complete demarcation line was identified. The depth of occurrence of the stromal demarcation line according to OCT was at the center of 305.73�Â�±41.08 �Î�¼m, nasally - 215.16�Â�±35.5 �Î�¼m and temporally 205,23�Â�±32.81 �Î�¼m. After 3 months, according to OCT, DL was detected in 6 cases (40%). The depth of its location was in the center of an average of 291.14�Â�±22.18 �Î�¼m, nasally - 201.15�Â�±27.5 �Î�¼m and temporally-190.13�Â�±43.58 �Î�¼m. In the periphery, the demarcation line was detected only in 5 cases (33%).


The optimal period for DL detection after corneal collagen cross-linking is 2- 12 weeks, and the depth of the stromal DL in the central area is deeper than peripheral ones.

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