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Straylight in keratoconus patients submitted to collagen cross-linking: conventional vs iontophoresis

Poster Details

First Author: G.Monaco ITALY

Co Author(s):    M. Gari   A. Scialdone                 

Abstract Details

Purpose:

The aim of the study was to compare the short-term variation of straylight in patients with keratoconus submitted to collagen corneal cross-linking (CXL).

Setting:

ASST Fatebenefratelli Sacco, Milan (Italy)

Methods:

The study was prospective, comparative, and randomized. Twenty eyes of 20 patients with progressive keratoconus were randomized into two groups: group A was submitted to conventional CXL (10 eyes), group B to iontophoresis CXL (10 eyes). All participants were analyzed pre-treatment, and post-treatment on 3 days, every week for 1 month, on two months and three months. The main outcome measure was the value of the logarithmic straylight value [log (s)] measured using a straylight meter (C-Quant�â�„�¢, Oculus Optikger�Ã�¤te GmbH, Wetzlar, Germany). We also evaluated the best corrected visual acuity (BCVA[logMAR]), the keratometry readings (K1, K2, Km, and Kmax), the manifest spherical equivalent refraction (D), the central corneal thickness (CCT, micrometers), and the endothelial cell density (ECD).

Results:

The retinal straylight in patients undergone to conventional CXL was pretreatment 1.16 (�Â�± 0,19), on 3 days after CXL was 1,44 (�Â�± 0,15), on 1 month was 1,28 (�Â�± 0,21) and on three months 1,15 (�Â�± 0,21); the retinal straylight in patients undergone to iontophoresis CXL was pretreatment 1,21 ( �Â�± 0,21), on 3 days after I-CXL was 1,33 (�Â�± 0,20), on 1 month was 1,09 (�Â�± 0,16) and on three months 1,05 (�Â�± 0,18) (p<0.05). No differences in BCVA, K readings, refraction, and ECD were found between groups. CCT was statistically reduced in the group A (p<0.05).

Conclusions:

The data indicate a statistically significant worsening of the straylight values starting from the third postoperative day (p<0.01) in both groups but patients submitted to iontophoresis CXL had an improvement in straylight compared to preoperative data.

Financial Disclosure:

NONE

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