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Iontophoretic collagen cross-linking for ectasia after LASIK and photorefractive keratectomy: long-term results

Poster Details

First Author: A.Cantemir ROMANIA

Co Author(s):    A. Alexa   D. Chiselita   D. Costin              

Abstract Details


To report the long-term results of iontophoretic collagen crosslinking (I-CXL) in ectasia after LASIK and photorefractive keratectomy (PRK).


Oftaprof Clinic, Iasi, Romania


Twelve eyes of 9 patients (7male, 2 female) with postoperative ectasia after LASIK ( 8 eyes) and PRK (4 eyes) were included. The mean age at the time of treatment was of 33 �Â�± 6 years and the mean follow-up was of 27 months (range, 12-47 months). The main outcome measures were uncorrected (UDVA) and corrected (CDVA) distance visual acuities, spherical and cylindrical refractions, maximum and minimum keratometry readings (Kmax and Kmin, respectively).


The UDVA and CDVA improved significantly, from 0.58 �Â�± 0.44 logMAR to 0.49 �Â�± 0.36 logMAR (P<0.05) and from 0.21�Â�± 0.23 logMAR to 0.17 �Â�± 0.13 logMAR, respectively (P<0.05). No eye lost 1 or more Snellen lines of UDVA or CDVA. The mean spherical and the mean cylindrical refraction decreased significantly at the last visit (P<0.05). The maximum K value decreased from 47.2 �Â�± 4.4 diopters (D) at baseline to 46.3 �Â�± 4.8 D at the last visit (P<0.05). The minimum keratomery was not significantly different at the last visit. No adverse events were found in any patient.


Iontophoretic collagen crosslinking yielded long-term stability in cases with corneal ectasia after LASIK and PRK without significant side effects. Improvements in visual acuity, cylindrical refraction, and maximum keratometry values occurred.

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