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Outcomes of ultrathin DSAEK performed in eyes with primary failure DMEK

Poster Details

First Author: S.Graffi ISRAEL

Co Author(s):    P. Leon   M. Busin                 

Abstract Details


To evaluate the outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with primary graft failure after Descemet stripping endothelial keratoplasty (DMEK), in an attempt at optimizing visual rehabilitation while minimizing the possibility of complications.


Ophthalmology Department, Villa Igea Private Hospital, Forli, Italy.


Charts of seventeen eyes that underwent UT- DSAEK for post-DMEK primary failure were reviewed retrospectively. In all cases, surgery was aimed at transplanting a graft, 100 �Â�µm or less in central graft thickness (CGT). Best spectacle-corrected visual acuity (BSCVA) and endothelial cell density (ECD) recorded 6 and 12 months postoperatively as well as CGT measured 6 months after UT-DSAEK.


When considering only eyes without co-morbidities (10 of 17), 6 months after UT-DSAEK, BSCVA was �â�‰�¥20/40 in all cases, �â�‰�¥ 20/25 in 8 eyes and 20/20 in 1 eye; 12 months after UT-DSAEK, BSCVA was �â�‰�¥ 20/25 in all cases and �â�‰�¥ 20/20 in 8 of 10 eyes. Mean ECD decreased from 2523�Â�±139 cells/ mm2 preoperatively, to 1813�Â�±401 cells/mm2 at 6 months and 1691�Â�±399 cells/ mm2 at 12 months postoperatively. CGT averaged 80.7�Â�±27.3 �Â�µm (range= 38 to128 �Â�µm) 6 months after UT-DSAEK. No intra- or postoperative complications were recorded.


UT-DSAEK proved effective in resolving corneal edema following DMEK primary failure and allowed all but 2 patients (80%) free of co-morbidities to achieve 20/20 vision in the absence of any type of complications.

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