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Prognostic value of intraoperative OCT with regard to graft adherence in endothelial keratoplasty

Poster Details

First Author: S.Dunker THE NETHERLANDS

Co Author(s):    M. Dickman   R. Nuijts                 

Abstract Details

Purpose:

To evaluate the prognostic value of intraoperative Optical Coherence Tomography (iOCT) with regard to postoperative graft adherence in endothelial keratoplasty.

Setting:

University Eye Clinic Maastricht, Maastricht, The Netherlands.

Methods:

Intraoperative OCT (RESCAN 700, Carl Zeiss Meditec, Germany) was performed at the end of 23 consecutive endothelial keratoplasties (ultrathin Descemet Stripping Automated Keratoplasty (UT-DSAEK), n=14; Descemet Membrane Endothelial Keratoplasty (DMEK), n=9). Scans were reviewed for graft adherence and compared with OCT scans (Casia SS-1000; Tomey, Japan) performed 1 hour, 1 day, 1 week and 1 month postoperatively.

Results:

Ten UT-DSAEK and seven DMEK grafts were approximated on iOCT to the host cornea of which nine UT-DSAEK (90%) and five DMEK grafts (71%) remained adherent postoperatively. One UT-DSAEK (10%) and two DMEK grafts (29%) detached significantly postoperatively despite adherence on iOCT. Five UT-DSAEK (36%) and two DMEK (29%) grafts showed some degree of incomplete graft approximation on iOCT, all of which were non-adherent postoperatively.

Conclusions:

Complete graft adherence at the end of surgery on iOCT is an effective predictor for graft attachment postoperatively to a greater degree for UT-DSAEK than for DMEK. Partial non-adherence visualized on iOCT is a good predictor for graft detachment post-operatively.

Financial Disclosure:

research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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