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Herpetic recurrent corneal erosion syndrome: opportunities of treatment by platelet-rich plasma

Poster Details

First Author: D.Maychuk RUSSIA

Co Author(s):    A. Loshkareva                    

Abstract Details


To estimate effectiveness of platelet-rich plasma (PRP) for treatment of herpetic recurrent cornea erosion syndrome with previously unsuccessful courses of reparative therapy.


Therapeutic Ophthalmology Department. Svyatoslav Fyodorov State Institution Eye Microsurgery Complex, 59A Beskudnikovskii Blvd, 127486, Moscow, Russia.


30 patients with recurrent corneal erosion syndrome were involved in this study. All patients had in anamnesis one-side Herpetic keratitis. First step of treatment included local and systemic antiviral therapy (Gancyclovir 0,15% and Valcyclovir pills 500mg.). After the therapy, vein blood mixed with Sodium citrate and Dextrosa anticoagulant, subjected to double centrifugation for 4 min. at 3500 rpm, was used. Patients were receiving PRP subconjunctival injections ones a week and instillations 6 times a day. Additional therapy included Dexpanthenol 5%. Treatment dynamics was assessed by Efron scale. For control was used the patients condition before PRP therapy.


The average index of the corneal lesion before treatment was 9.6 points. After the 1st and 2nd procedure average lesion index was 8.4 and 6.0 points respectively. After 3 weeks, complete epithelization was observed in 23 patients. 5 patients showed a gradual disappearance of the epithelial defects after 5-6 procedures. 2 patients did not show any response.


Comparative analysis with standard methods of therapy featured positive dynamic of PRP treatment.

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