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Herpetic recurrent corneal erosion syndrome: opportunities of treatment by platelet-rich plasma

Poster Details

First Author: D.Maychuk RUSSIA

Co Author(s):    A. Loshkareva                    

Abstract Details

Purpose:

To estimate effectiveness of platelet-rich plasma (PRP) for treatment of herpetic recurrent cornea erosion syndrome with previously unsuccessful courses of reparative therapy.

Setting:

Therapeutic Ophthalmology Department. Svyatoslav Fyodorov State Institution Eye Microsurgery Complex, 59A Beskudnikovskii Blvd, 127486, Moscow, Russia.

Methods:

30 patients with recurrent corneal erosion syndrome were involved in this study. All patients had in anamnesis one-side Herpetic keratitis. First step of treatment included local and systemic antiviral therapy (Gancyclovir 0,15% and Valcyclovir pills 500mg.). After the therapy, vein blood mixed with Sodium citrate and Dextrosa anticoagulant, subjected to double centrifugation for 4 min. at 3500 rpm, was used. Patients were receiving PRP subconjunctival injections ones a week and instillations 6 times a day. Additional therapy included Dexpanthenol 5%. Treatment dynamics was assessed by Efron scale. For control was used the patients condition before PRP therapy.

Results:

The average index of the corneal lesion before treatment was 9.6 points. After the 1st and 2nd procedure average lesion index was 8.4 and 6.0 points respectively. After 3 weeks, complete epithelization was observed in 23 patients. 5 patients showed a gradual disappearance of the epithelial defects after 5-6 procedures. 2 patients did not show any response.

Conclusions:

Comparative analysis with standard methods of therapy featured positive dynamic of PRP treatment.

Financial Disclosure:

NONE

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