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Corneal biomechanical changes after uneventful phacoemulsification in type 2 diabetic and non-diabetic patients

Poster Details

First Author: C.Madeira PORTUGAL

Co Author(s):    J. Beato   J. Esteves-Leandro   D. Reis   M. Falcao   A. Carneiro   F. Falcao-Reis     

Abstract Details

Purpose:

To compare corneal biomechanical changes after uneventful phacoemulsification cataract surgery between type 2 diabetic (DM) and non-diabetic patients.

Setting:

Department of Ophthalmology, Centro Hospitalar S�Ã�£o Jo�Ã�£o, Porto, Portugal.

Methods:

Forty-four diabetic (44 eyes) and 44 (44 eyes) age and sex-matched non-DM controls with age-related cataract were enrolled in this prospective observational study. Corneal histeresis (CH), corneal resistance factor (CRF) and corneal-compensated intraocular pressure (IOPcc) were evaluated using the Ocular Response Analyzer�Â�® (ORA); central corneal thickness (CCT) was recorded using the Pentacam HR. Patients were evaluated preoperatively and 1 and 6 months after surgery.

Results:

In both groups, there was a significant postoperative IOPcc reduction 6 months after surgery (p<0.001). In the DM group, CH was observed to be significantly lower than preoperative value at 1 (p=0.040) but not at 6 months follow-up (p=0.437); while it did not change significantly in the non-DM group (p>0.05). CRF was observed to be significantly lower than preoperative value at 1 and 6 months in both groups. Multivariate linear regression showed that postoperative CH change was significantly associated with preoperative CH (p<0.001), preoperative IOPcc (0.004) and IOPcc change (p<0.001); whereas CRF change was only correlated with preoperative CRF (p<0.001).

Conclusions:

This study shows comparable corneal biomechanical changes between DM and non-DM groups, and suggest that the CH and CRF respond differently to cataract surgery.

Financial Disclosure:

NONE

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