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Retreatment rates for recurrent corneal erosion syndrome following excimer laser phototherapeutic keratectomy

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Session Details

Session Title: Moderated Poster Session: News on Cornea

Venue: Poster Village: Pod 1

First Author: : S.Naylor UK

Co Author(s): :    R. Darbyshire   S. Anand   A. Morrell   J. Ball     

Abstract Details


Recurrent corneal erosion syndrome (RCES) is a common clinical disorder associated with debilitating ocular symptoms and significant visual morbidity1. The condition is chronically recurrent in nature and is characterised by a frustratingly poor response to conservative management. Excimer laser Phototherapeutic Keratectomy (PTK) is reserved for severe and refractory cases. Literature regarding re-treatment rates following primary treatment is lacking. Our study investigates the rate of recurrence following first PTK and risk factors for treatment failure.


St James's University Teaching Hospital, Leeds, West Yorkshire, United Kingdom


Patients undergoing PTK between 1st January 2015 and 31st December 2015 were retrospectively identified. The protocol involved corneal epithelial debridement ± ethanol, followed by PTK with a 12μm ablation depth and 8μm zone. Post-operative topical management involved G. ofloxacin 0.3% QDS for 7 days, prednisolone minims 0.5% QDS for 2 weeks, ongoing G. sodium hyaluronate 0.15% QDS. 2 sachets of proxymetacaine were provided for the immediate post-operative period.


68 PTK treatments were undertaken in the 12 month period. Indications included 10 cases of non-dystrophic RCES, 22 traumatic RCES, 34 dystrophic RCES and 2 other (one post penetrating keratoplasty and one Salzmann nodular degeneration). 9 (13%) experienced a further flare. 7 of these occurred within 12 months of the initial PTK treatment. 1 occurred after intravitreal anti-VEGF treatment. 6 of the 9 treatment failures were associated with poor compliance with post-operative topical medication.


PTK successfully resolved 87% of RCES cases which had failed medical management. The 13% treatment failure was similar to other studies published in this area. Poor compliance with topical mediations is a previously unidentified risk factor for treatment failure.

Financial Disclosure:


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