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Corneal endothelial cell loss after cataract surgery: long-term (≥ 10 years) results of prospective study

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Session Details

Session Title: Presented Poster Session: Complications Management in Cataract Surgery

Venue: Poster Village: Pod 1

First Author: : S.Kim SOUTH KOREA

Co Author(s): :    Y. Han   J. Choi           

Abstract Details

Purpose:

To report the long term results of corneal endothelial loss following uneventful cataract surgery and investigate the factors associated with decrease in corneal endothelial cell density (ECD)

Setting:

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center

Methods:

This prospective study enrolled the patients from January, 2014 to February, 2017 and reviewed 83 eyes of 49 patients who had undergone cataract surgery more than 10 years before by single surgeon with same intraocular lens. Long-term (≥ 10 years) changes of ECD after uneventful cataract surgery were evaluated with specular microscope. To analyze the correlating factors of ECD loss, preoperative biometric variables including cataract grade, anterior chamber depth, axial length, types of ophthalmic viscosurgical device, and postoperative corneal edema were evaluated.

Results:

Preoperative and long-term postoperative ECD were 2793±351.09 and 2148±478.38 cells/mm2 (mean±SD), respectively. Mean follow up period was 11.08±1.06 years and 10-year ECD loss rate was 20.62±13.63%. Preoperative nuclear firmness was statistically the most correlated with increased long term ECD loss rate (β coefficient: 0.395; 95% confidence interval, 106.77-295.95, P<0.001). Degree of postoperative corneal edema was a significant predictive factor of increased long term ECD loss in cataract surgery (β coefficient: 0.31; 95% confidence interval, 53.18-234.72, P=0.002).

Conclusions:

Preoperative nuclear firmness and postoperative corneal edema are the predictors of the long-term (≥ 10 years) endothelial cell loss after cataract surgery.

Financial Disclosure:

NONE

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