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A quantitative analysis of viral load in patients with adenovirus keratoconjunctivitis

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Session Details

Session Title: Moderated Poster Session: New and Interesting

Venue: Poster Village: Pod 1

First Author: : P.Isik TURKEY

Co Author(s): :    N. Kocu   E. Erdem   F. Yarkin   M. Yagmur   R. Ersoz  

Abstract Details


To investigate the relationship between the clinical severity and viral quantitative load detected by polymerase chain reaction (PCR) in adenoviral keratoconjunctivitis.


Cukurova University Faculty of Medicine, Ophthalmology and Virology Departments


Conjunctival swab samples were taken for real-time PCR analysis from patients with clinically suspected adenoviral conjunctivitis. Patients were divided into two groups as low positive (<100,000 copies) (Group 1) and high positive (> 1,000,000 copies) (Group 2) according to the number of DNA copies detected. The two groups were compared in terms of clinical features.


Twenty-nine eyes of 29 patients (17 female, 12 male), 8 in Group 1 and 21 in Group 2 were included in the study. The mean age was 36 16 ranged from 1 to 73 years. Clinical findings in Group 1 and 2 were; eyelid edema %75 and %90, chemosis %25 and %67, conjunctival hemorrhage 71% and 100%, conjunctival follicles 63% and 71%, pseudomembran 38% and 62%, punctate keratopathy 50% and 57%, corneal subepithelial deposit % 25 and 48% respectively.


In this study, it was observed that the clinical presentation was more severe in cases with a high virus load. For these severe cases contagiousness may be more likely, so preventive measurements should be keep in mind.

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