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Study of meibomian gland dysfunction and hypercholesterolemia

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Session Details

Session Title: Presented Poster Session: Quality of Vision/Miscellaneous

Venue: Poster Village: Pod 3

First Author: : A.Segi INDIA

Co Author(s): :    K. Jha   K. Srikanth           

Abstract Details

Purpose:

To study the association of Meibomian Gland dysfunction (MGD) with hypercholesterolemia in adults aged 20-60 years age in a hospital based setting

Setting:

Ophthalmology out-patient department in a tertiary care hospital in South India

Methods:

We studied one hundred twenty individuals aged 20-60 years divided into two groups; sixty cases of MGD and no known hypercholesterolemia; sixty controls with neither MGD nor hypercholesterolemia. Examination included anterior segment examination, tear film break-up time , Schirmer’s test and assessment of meibomian gland function. MGD was graded based on quality of meibum secretion and meibomian gland function (expressibility). Other investigations included lipid profile, random blood sugar, serum creatinine and body mass index (BMI).

Results:

Hypercholesterolemia (i.e. ≥ 200 mg/dl) was 39 (65%) and 31 (51.67%) in cases and controls, respectively. Hypercholesterolemia (i.e. ≥ 200 mg/dl) was found in 17 (44.7%) cases with grade 2 meibomian gland function (i.e. expressibility) (p=0.038) and 26 (68.4%) cases with grade 2 meibomian gland secretion (p = 0.037), thus showing that it is statistically significant.

Conclusions:

Our results suggest that patients with moderate MGD (i.e. grade 2 expressibility and secretion) have elevated level of total cholesterol (i.e. serum cholesterol level ≥ 200 mg/dl.

Financial Disclosure:

NONE

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