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Evaluation of tear film osmolarity and other signs of dry eye in patients with keratoconus with and without intracorneal ring segment implantation

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Session Details

Session Title: Presented Poster Session: Cornea III

Venue: Poster Village: Pod 2

First Author: : C.Peris-Martinez SPAIN

Co Author(s): :    E. Fernandez-Lopez   M. Roig-Revert   M. Garcia-Domene   A. Diez-Ajenjo     

Abstract Details

Purpose:

To evaluate the quantity and quality of tear film before and after the implantation of intracorneal rings in patients with keratoconus (KC) and compare it with healthy subjects.

Setting:

FISABIO Oftalmología Médica (FOM). Cornea and Anterior Segment disesases Unit University of Valencia

Methods:

A total of 23 KC eyes (KC group, n = 23 eyes), 29 KC eyes with intracorneal ring implants (KC with ICRS group, n = 29 eyes) and 23 healthy subjects as a control group (CG, n= 23 eyes) were enrolled in this study. The parameters studied were: Osmolarity (TearLabTM) and other signs of drye eye like tear break-up time (TBUT), Schirmer I test with no anesthetic, ocular surface staining characteristics with lysamine green, Visual Analog Scale. Symptoms of discomfort, Eye Surface Disability Questionnaire with ocular surface disease index (OSDI®). Statistical significance was set at p < 0.05.

Results:

The differences in osmolarity evaluated, were statistically significant (p < 0.05) comparing the three groups. Mean osmolarity in KC group were 320.8 ± 10.35 mOsm/l in the KC group, 295.34 ± 10.2 mOsm/l in the KC with ICRS group and 299.13 ± 7.42 mOsm/l in the CG. We found no statistically significant differences in TBUT between groups and lysamine staining between groups.

Conclusions:

Intracorneal rings may play a role in improving the quality and distribution of the tear film in patients with keratoconus. This may lead to a greater ocular comfort, reducing the rubbing habit and thus slow the progress of the disease closing a vicious circle.

Financial Disclosure:

NONE

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