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A rare case of spindle cell carcinoma of the cornea and conjunctiva

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Session Details

Session Title: Presented Poster Session: Cornea II

Venue: Poster Village: Pod 2

First Author: : N.Arslan TURKEY

Co Author(s): :    M. Kosker   C. Gurdal   F. Aksoy Khurami   U. Han     

Abstract Details

Purpose:

We wanted to report a 75-year-old female presented to our clinic with a painful bulging mass over the right cornea. In slit-lamp biomicroscopy, there was an elevated, fixed vascularized conjunctival mass covering the right cornea with extension to the nasal bulbar and upper palpebral conjunctiva. The best corrected visual acuity was light perception in the right eye and 20/30 in the left eye.

Setting:

Dışkapı Yıldırım Beyazıt Education and Research Hospital Department of Ophthalmology

Methods:

The patient underwent a total excision of the lesion including conjunctival and corneal parts and covered the ocular surface with 2 layers of amniotic membrane. We started topical MMC 0.2 mg/ml (0.02%) four times daily which she has been on for 2 weeks.

Results:

In the histopathologic evaluation conjunctival squamouse epithelium which has significant polarity loss, nuclear enlargement, hyperchromasia and pleomorphism was detected. Most of the areas consistent with spindle cell carcinoma including focuses of poorly differantiated squamous cell carcinoma with brisk mitotik activity. Post-operative positron emission tomography–computed tomography (PET/CT) revealed increase in 18F FDG in the right conjunctival & left hilar area.The patient refused to undergo further investigation or attend controls at the medical oncology department .

Conclusions:

Diagnosis of spindle cell carcinoma is challenging as it is a rare condition with low insidence and because of overlapping histopathological features with other spindle cell tumors. A detailed pathological examination is very important for the decision of proper treatment.

Financial Disclosure:

NONE

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