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Recovery of corneal clarity after DMEK followed by re-bubbling versus uneventful DMEK

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Session Details

Session Title: Presented Poster Session: Cornea I

Venue: Poster Village: Pod 3

First Author: : K.Droutsas GREECE

Co Author(s): :    G. Kymionis   E. Giallouros   D. Papaconstantinou   D. Brouzas   W. Sekundo   A. Lazaridis

Abstract Details


To evaluate corneal densitometry (CD) after Descemet membrane endothelial keratoplasty (DMEK) followed by Rebubbling versus uneventful DMEK.


Department of Ophthalmology, Philipps-University, Marburg, Germany


Medical records of 130 consecutive DMEK cases (118 patients) were reviewed. After excluding cases with prior corneal surgery, primary or secondary graft failure, two groups were formed. Group 1 (n=32): eyes undergoing DMEK with subsequent Rebubbling due to postoperative graft detachment and group 2 (n=80): eyes undergoing DMEK without further procedures. Scheimpflug CD of the optically relevant (0-2mm and 2-6mm) and peripheral (6-10mm) zone, endothelial cell density (ECD), central corneal thickness (CCT) and corneal volume (CV) were evaluated preoperatively and at 3, 6, and 12 months postoperatively.


Central CD (zones 0-2mm and 2-6mm) decreased significantly in both groups (P≤0.011). CD at the periphery(zone 6-10mm) decreased significantly in group 1, however not in group 2 (P=0.222). CD was significantly higher in group 1 at 3 months (zones 2-6 and 6-10mm) (P=0.037 and 0.035, respectively). ECD was not significantly higher in group 1 (P≥0.073). Finally, CCT and CV did not show a significant difference between the two groups.


The presented data suggest that Rebubbling allows corneal clearance to similar levels as uncomplicated DMEK while causing similar endothelial cell loss.

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