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Comparison of retinal nerve fiber layer and ganglion cell complex thicknesses in patients with primary open-angle glaucoma

Poster Details

First Author: F.Ozturk TURKEY

Co Author(s):    M. Turkyilmaz   M. Can   T. Takmaz        

Abstract Details

Purpose:

To compare the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) layer thicknesses in patients with primary open angle glaucoma (POAG), ocular hypertension (OHT) and healthy subjects using spectral domain optical coherence tomography (SD-OCT).

Setting:

Yildirim Beyazit University, Ataturk Training and Research Hospital, Department of Ophthalmology

Methods:

Cross-sectional comparative study. 19 POAG, 16 OHT and 14 healhty subjects were enrolled in the study.All patients were subjected to full opthalmic examinations,RNFL and GCC layer thicknesses were measured with SD-OCT.

Results:

Twenty four eyes of 19 patients with POAG, 26 eyes of 16 patients with OHT and 28 eyes of 14 healthy subjects were included with a mean age of 62.4±8.4, 58.7±9.5, 49.6±6.6 years respectively. There were no significant differences in age, gender, or refraction between the groups. There were no statistical significant correlation between POAG ang NTG group in any quadrants, however superior and nasal quadrants were statistically thinner at POAG and NTG groups compared to control group. The mean GCC values were not statistically significant at any quadrant of all groups.

Conclusions:

Early glaucomatous changes can be detected by RNFL before significant optic nerve head findings occur. GCC alone has a limited ability to diagnose glaucomatous damage earlier than conventional methods.

Financial Disclosure:

NONE

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