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Encapsulation of glaucoma tube shunt devices in Sturge-Weber syndrome and

Poster Details

First Author: M.Kamel SAUDI ARABIA

Co Author(s):    S. Eissa              

Abstract Details

Purpose:

Purpose: The subconjunctival bleb is critical to the success of a glaucoma tube shunt device and maintaining aqueous outflow.1 Patients with Sturge-Weber syndrome (SWS) and glaucoma have abnormal subconjunctival tissues with increased vascularity,2 which may affect bleb formation and function. The objective of this study is to compare the relative rates of failure of tube shunt devices due to encapsulation (bleb failure) in children with glaucoma related to SWS and other types of glaucoma

Setting:

Magrabi hospital Aseer KSA

Methods:

A retrospective chart review was undertaken of all children having undergone tube shunt implantation for glaucoma at the Children’s Hospital of Philadelphia from 2000-2010. Eyes with failure of the tube shunt were classified by the etiology of tube failure and glaucoma diagnosis.

Results:

Records of 57 eyes of 46 patients were reviewed. The glaucoma diagnoses in this group were as follows: 18 aphakic, 12 SWS, 12 congenital, 4 uveitis, 4 Axenfeld anomaly, 3 aniridic , 1 juvenile, and 1 associated with Stage IV retinopathy of prematurity. The rate of failure due to encapsulation was 75% (9 of 12 eyes) in eyes with SWS versus 18% (8 of 45 eyes) in all other diagnoses (p=0.00003, chi-squared test). Failure occurred at a mean of 3 years after implantation in SWS (range 10 months-6 years), and at 1 year in all other diagnoses (range 3 months-3.3 years).

Conclusions:

Discussion: Tube shunt devices fail from encapsulation frequently in pediatric glaucoma patients. Late failure due to encapsulation appears more frequently in SWS than in other types of pediatric glaucoma. This increased rate of encapsulation may be related to differences in episcleral and subconjunctival healing and wound repair, possibly related to episcleral vascular abnormalities. Conclusion: SWS is associated with a higher rate of late failures of glaucoma tube shunt devices from encapsulation in comparison to other pediatric glaucomas.

Financial Disclosure:

NONE

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