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Comparison of accelerated with standard corneal crosslinking in terms of the efficacy and visual performance

Poster Details

First Author: N.Kahraman TURKEY

Co Author(s):    K. Gumus              

Abstract Details

Purpose:

To compare the efficacy and visual performance of accelerated and standard corneal collagen crosslinking (CXL) for progressive keratoconus after one year of follow-up.

Setting:

Erciyes University Faculty of Medicine, Department of Ophthalmology, Kayseri, Turkey

Methods:

Thirty-four eyes of 17 (10 female / 7 male) patients with progressive keratoconus were included in this study. While one eye was treated with the standard CXL, the other eye was treated with the accelerated CXL (10 min – 9mW). All patients were monitored regularly (1., 3., 6., 9., 12.month) after the uneventful CXL. Uncorrected and best spectacle corrected visual acuity, topographic refractive indices, total ocular and total higher order (HO) aberrations, point spread function (PSF) (the Strehl ratio) were noted at all visits.

Results:

The mean age was 23.6 years. There were no statistically significant differences in terms of uncorrected and best spectacle corrected visual acuity values and topographic refractive indices in two groups. In standard CXL, flat and steep keratometry and Kmax values revealed statistically significant decrease after one year (p= 0.001, p= 0.042, p= 0.019). Whereas, in accelerated CXL, these values were not significantly different from baseline after one year (all p> 0.05). When total ocular and HO aberrations, PSF values were analyzed, there was no statistically significant difference between the baseline and 1-year results of measurements in both groups.

Conclusions:

Both standard and accelerated CXL seem to be effective for stabilizing progressive keratoconus. However, it is obvious that the eyes treated with standard CXL exhibited significantly more reduction in keratometric values.

Financial Disclosure:

NONE

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