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Descemet membrane endothelial keratoplasty (DMEK). Review of the first 23 cases

Poster Details

First Author: B.Kandemir TURKEY

Co Author(s):    T. Ayyildiz   O. Salkaci   O. Rodop Ozgur   U. Calli   Y. Ozturk  

Abstract Details

Purpose:

To evaluate the functional and morphologic outcomes of the first 23 cases who underwent descemet membrane endothelial keratoplasty (DMEK) at Eye Clinic of Dr. Lütfi Kırdar Training and Research Hospital in patients suffering from decreased vision secondary to endothelial cell dysfunction

Setting:

Eye Clinic of Dr. Lütfi Kırdar Training and Research Hospital, State Hospital, a tertiary referral center. İstanbul

Methods:

Retrospective, single center, consecutive case series. Triple DMEK (n=5), DMEK (n=18) and re-DMEK (n= 2) was performed in 23 consecutive eyes of 23 patients. Main outcome measures included the number of postoperative air injections required for graft attachment, postoperative best corrected visual acuity (BCVA (logMAR)),central corneal thickness (CCT), endothelial cell density (ECD) and re-DMEK and endothelial rejection rates.

Results:

Out of 23 cases 5 required 1time and 2 required 2 times, 1 required 3 times re-bubbling for partial graft detachment , mean BCVA increased from 2. 25 +/- 0.73 logMAR preoperatively (n=24) to 0.08 +/- 0.01 logMAR at 6 months (n= 12) after surgery. Mean ECD of donor corneas decreased from 3003.58 +/- 225.44 cells/mm2 (n=23) to 1319.16 +/- 260.49 cells/mm2 after 6 months (n= 12). Mean CCT decreased from 912. 04 +/- 128. 59 µm (n=23) to 514. 75 +/- 12.45 µm after 6 months (n=12). Graft rejection occurred only in one patient

Conclusions:

DMEK; in cases of endothelial cell dysfunction, with or without combined cataract surgery and IOL implantation, have favorable functional and morphological outcomes with minor complications

Financial Disclosure:

NONE

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