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Correlation of endothelial cell density with corneal tomographic parameters in eyes with keratoconus

Poster Details

First Author: B.Bozkurt TURKEY

Co Author(s):    M. Yilmaz   A. Mesen   U. Kamis   B. Ekinci-Koktekir   S. Okudan  

Abstract Details

Purpose:

To evaluate the correlation of corneal endothelial cell count with corneal tomographic parameters in eyes with keratoconus.

Setting:

University Clinic

Methods:

Four hundred eyes of 249 patients with keratoconus were enrolled in the study. Corneal tomography using a combined placido disc and Scheimpflug technology (Sirius, CSO, Italy) and specular microscopy (Nidek Confoscan 4) were performed to all patients. The correlations between endothelial cell density (ECD) and tomographic parameters (K1, K2, minimum central corneal thickness (CCT), apical CCT, anterior elevation) were measured using Pearson correlation and a p value less than 0.05 was accepted as statistically significant.

Results:

There were 118 male and 131 female with a mean age of 25.82±8.22 (range between 11 and 58 years) in the study. The correlations between ECD and keratometric values, anterior and posterior elevation parameters and CCT were weak, but statistically significant (r= 0.17-0.24) (p<0.05). Mean ECD values were 2360.88 cells/mm2, 2493.45 cells/mm2 and 2590 cells/mm2 in corneas with minimum CCT values less than 400 µm, 400-450 µm and greater than 450 µm, respectively (p<0.001).

Conclusions:

In keratoconus, ECD seems to decrease with the progression of the disease in respect to tomographic parameters and CCT measurements.

Financial Disclosure:

NONE

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