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To compare the safety profile of single use intracameral cefuroxime in cataract surgery

Poster Details

First Author: B.Aslan TURKEY

Co Author(s):                  

Abstract Details

Purpose:

Aprokam® (intracameral single dose cefuroxime) has been approved in the EU for the prophylaxis of postoperative endophthalmitis after cataract surgery. We looked for the safety profile of Aprokam® (intracameral cefuroxime) that doesn’t require any further dilution.

Setting:

Tobb Etu Hospital- Ankara Turkey

Methods:

In this controlled trial, 20 patients received 1 mg of cefuroxime (1 mg in 0.1-mL solution) -single use- with normal saline - given intracamerally during cataract surgery. Central endothelial cell density (ECD) and macular center thickness (MCT) and center corneal thickness (CCT) were determined by specular microscopy and ocular coherence tomography and corneal-ultrasound pachymetry respectively, before and 1 week after surgery.

Results:

There were no statistical significant differences in the changes of ECD, MCT and CCT in the eyes receiving intracameral single use cefuroxime. The use of single dose intracameral cefuroxime at the time of cataract surgery had no significant effect on ECD, MCT and CCT postoperatively.

Conclusions:

It is safe to use Aprokam® (intracameral cefuroxime). Prophylaxis with single dose intracameral cefuroxime at the recommended dose appears to be well tolerated in patients undergoing cataract surgery.

Financial Disclosure:

One or more of the authors gains financially from product or procedure presented

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