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Clinical features of steroid induced cataract in patients with newly diagnosed steroid induced ocular hypertension and glaucoma in Azerbaijan

Poster Details

First Author: F.Aghayeva AZERBAIJAN

Co Author(s):    E. Kasimov              

Abstract Details

Purpose:

To investigate the clinical features of steroid induced cataract (SC) in patients with newly diagnosed steroid induced ocular hypertension (SOH) and glaucoma (SG) by taking into account the modality of steroid treatment (ST).

Setting:

SC and SOH/SG are well known complications of steroid therapy. The rate of corticosteroid induced cataract varies from 11 to 15% in patients on systemic steroids. The information provided on incidence and features of SC in patients with diagnosed SOH or SG is quite limited.

Methods:

This prospective study involved 40 patients (74 eyes) with different diseases, who had received local (31 - 77,5% - patient), systemic (7 – 17,5% - patients) or combined (2 – 5% - patients) ST. Prevalence of SC, intraocular pressure (IOP), percentage of cases required antiglaucomatous surgery were evaluated.

Results:

SOH and SG were primary diagnosed in 22(55%) and 18(45%) patients,respectively.The mean baseline IOP was 33,62±8,26 mmHg.Different grades of SC were revealed in 16(21,62%) eyes of 8(20%) patients with SG.It should be mentioned that all these patients have received ST during 3 years or more.We have not revealed any reliable correlation between the prevalence and risk of SC formation and method of ST but the duration of steroid therapy was longer in patients with diagnosed SC who had been on systemic steroids.İn 18,9% cases the IOP could not be controlled by antiglaucomatous medications and antiglaucomatous surgery was required.

Conclusions:

Obtained data show that risk of cataract formation is higher in patients on ST with duration more than 3 years. This report once again confirms the necessity of permanent monitoring of all patients treated with steroids as it makes possible to prevent the most cases of SC and SG.

Financial Disclosure:

NONE

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