ESCRS Homepage

April 2003
Eye to Eye Supplement Compliance : The Hidden Challenge of Glaucoma Management
IN THIS ISSUE

Safer refractive IOLs to boost vision options for ametropes


EGS to publish updated guidelines for diagnosis and management of glaucoma

Topical beta-blockers cause respiratory obstruction for one in every 55 patients

Immediate treatment halves risk of open-angle glaucoma progression, EMGT report reveals

Nothing between them as randomised Canadian SLT/ALT study releases preliminary results

Latanoprost does not cause ocular pathology by inducing ultrastructural iris changes, says study

One-piece ‘floating’ refractive implant could prove a secure new option for the correction of myopia

Battlelines clearly marked out as trabeculectomy and drainage implant surgery go head to head

New visual field testing strategies to banish patient boredom and facilitate earlier detection

Latanoprost remains leader of the drops but proponents of competing drugs line up to bid for alternative

Data drought ends as surge of clinical results explains effects of treatments on the development of glaucoma

Zyoptix system produces encouraging results in US for the correction of myopia

Refractive IOL and laser bioptics broaden possibilities for highly ametropic patients, says specialists

How the eye’s natural adaptive mechanism
can compensate for corneal aberrations

Handheld GPS device helps blind steer safely through the metropolitan jungle

New classification system to assist in diagnosis and treatment of limbal stem cell disease

Lasik on top in ultimate test as daredevil climbers reach Mount Everest’s summit in 29,000ft hike

PHMB-containing antiseptics ‘may offer alternative’ to iodine
perioperative agents, say researchers

High intensity headlights could cause road
accidents by dazzling oncoming drivers

Oral sildenafil causes inconsistent changes in
choroidal vascular congestion, study shows

HALTK’s alternative to PK could be gateway to restoring corneal clarity

Doctors warn against ditching specs Superman-style as fears remain on safety of paediatric Lasik

Povidone-iodine offers inexpensive alternative for paediatric conjunctivitis

Getting to grips with ocular tissue is crucial to PK success in children

New device brings virtual vision to the blind

Toric IOLs improve on previous designs with less rotation and more patient satisfaction

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Reflections on Refractive Surgery
In Your Good Books
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Regulatory Matters



New visual field testing strategies to banish patient boredom and facilitate earlier detection

Laszlo Dosa
in Miami, Florida

THE initials SITA, SWAP and FDT have come to characterise the current status of new strategies in visual field testing methods.
A usually laborious procedure, visual field testing is tiring for the patient who has to sit for 45 minutes and respond whenever they see a light flash very quickly in different places. And it is not so much the patient than the neurological system that fatigues, Douglas R Anderson MD noted at a symposium on controversies in glaucoma management.

Swedish Interactive Thresholding Algorithm (SITA) is an effort to perform field testing in a way that is easier on the patient. Developed by a group of Swedish mathematicians and ophthalmologists, SITA is aimed at making the testing more efficient.
It is an interactive thresholding algorithm in the sense that it makes use of the information it is gathering as it goes along to enable it to decide what to do next in the test, as opposed to simply having the test algorithm as it proceeds.
He said perhaps the greatest merit of SITA- standard is that the test is fast, (half the time of the previous standard) and is as acurate as other tests.

The SITA-standard test is now the routine method used by many glaucoma specialists. SITA also has a fast version, SITA-FAST. The SITA fast version should not be a practice standard, but can be used for patients who do not do field tests well. The SITA-fast version is difficult to handle for inexperienced field takers which can be a problem when used for screening, said Dr Anderson.

It should not be a practice standard, but can be used for patients who do not do field tests well. Even though the five-year-old test is already quite widely used, it is difficult to handle for inexperienced field takers, which can be a problem when used for screening, said Dr Anderson.

Short Wavelength Automated Perimetry (SWAP) was initially developed to highlight visual pathways thought to be particularly involved in glaucoma.
It is employed to try to look for very early subtle defects by testing only one part of the visual system, namely the part that sees blue. When a white light is shone, which is done in standard polarimetry, SWAP sees the light if the patient’s blue, red and green systems are working.

If only one of those three systems is not operating properly, the person still sees the white light. But if you show him a blue light, if the blue system is out, then it won’t show. In so doing the test bypasses redundancy of visual system neurons, Dr Anderson explained.

Frequency Doubling Technology (FDT) is used to isolate a particular pathway, just like the SWAP does. It is a new technique, still under evolution and improvement, and is used mostly for detection but it is also capable of thresholding.
“Frequency doubling is a phenomenon in which if you alternate bars of white and black so that if the white goes off at the same time the white goes on, you actually see twice as many bars as there really are.

“That may not be relevant but at least it stimulates one of the systems and it is just a different system. It’s not the blue system, just a different one. By isolating one system, presumably it can be more effective,” he said.
The new field testing systems offer some hope of earlier detection of glaucoma. Recent clinical research indicates that the systems are starting to live up to their promise.

For example, a study at the University of California in San Diego showed that SWAP screening could detect filed defects two to five years earlier than standard visual field testing. Another study showed that FDT could identify 70% of patients with obvious glaucomatous optic neuropathy. Standard perimetry only identifies 6% of these patients.

Earlier detection of glaucoma offers clinicians the chance to intervene earlier in the course of glaucoma, possibly reducing the rate of progression of the disease.
These same systems could prove useful in determining the effects of treatment over time, a boon for those conducting clinical trials. The new screening systems also offer a wealth of useful information to researchers who are studying the pathology of the disease.

Douglas R Anderson MD
Bascom Palmer Eye Institute, Miami, Florida, US
Email: danderson@med.miami.edu

 

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