ESCRS Homepage

September 2003
IN THIS ISSUE

New device creates alcohol-free epithelial flaps to improve healing and reduce haze


New IOL fixes suture-free in capsule-less eyes

Researchers race to produce bionic vision

Implantable telescope shows promise in AMD

New IOL Tackles Anterior-Capsule-Related Complications

Prospective study shows water jet phaco as effective as ultrasound for majority of cataracts

Laser microkeratome may reduce flap complications and improve visual outcome

Customised wavefront-guided ablation: exciting technology but beware the hype

Multifocal ablation results promising in presbyopia

In line phaco-filter aims to improve safety

Studies link genes to age-related cataract

Human genome project yielding clues to the aetiology of many ophthalmic disorders

New IOL 'adjusts' postoperatively to target refraction

Cold phaco heats up as new era dawns

Hartmann-Shack aberrometer finds new application in evaluation of nuclear cataract

Refractive surgery can improve quality of life - survey

Large retrospective study supports early intervention in paediatric cataracts

Study tracks blade influence on flap thickness

Study shows multifocal IOL implantation provides good binocular vision

Study revives hyperopic LASIK centration debate

Phakic IOL better than LASIK for high myopia

Getting to grips with ocular herpes

New rounded IOL edge design reduces glare

25-gauge vitrectomy needle speeds surgery

Indications for botulinum toxin treatment continue to expand

Experts debate value of customised ablation

FEATURES
From The Editor
Reflections on Refractive Surgery
Prime Site
Bio-ophthalmology
Eye On Travel
Collectors Eye
Regulatory Matters


New rounded IOL edge design reduces glare

Barbara Boughton in San Francisco

GLARE is significantly higher in double square-edged IOL lens designs than in hybrid lens edge designs, suggests laboratory research presented at the annual meeting of the ASCRS.

Bradley Black MD and colleagues used a non-sequential ray tracing to model the impact of IOL edge design on the distribution and intensity of reflected and transmitted light rays. They found that the intensity of light with both transmitted and reflected glare is much greater with the double square edge IOL design.
"With the OptiEdge IOL (Sensar, AMO), light rays are dispersed over the retina, which reduces the intensity of glare-and that's what's important in whether a patient notices haloes or arcs of light," he reported.

The posterior squared-off edge has long been prized because of its ability to prevent opacification of the posterior capsule through the mechanical barrier effect. But research by Jack Holladay MD and others has also described the dysphotopsia that occurs with the squared off edge, including glare, halos, shadows and arcs of light.
"Rounding the edge of the optic causes greater dispersion of the internally reflected rays of light, reducing intensity of edge glare by 90 percent," Dr Black said.

Just how this translates clinically, however, is still an open question. Dr Black noted that he has implanted many IOLs with double-square-edge design and hasn't had to explant any. However, after several months the investigators noticed a marked reduction in frequency of complaints about glare from patients who received lenses with the OptiEdge design.
When light rays hit a squared lens edge, the rays are displaced to a nonvisiotopic part of the retina, forming a disturbed image. Transmitted light rays are directed to areas other than the source image, while reflected rays curve away. Both transmitted and reflected light can contribute to glare.

The investigators found that when light hits the double-squared edge lens at 23 degrees, there was little edge glare. But at 35 degrees, one begins to see arcs and intense tightly focused spots, though very little transmission glare. Meanwhile, at 55 degrees, transmitted as well as reflected glare becomes significantly more evident.
In the OptiEdge's hybrid lens design, in which the posterior edge is squared off but the anterior edge is rounded, the investigators did not see any internally reflected rays at 23 degrees.

"Once you get to 35 degrees with the OptiEdge, you see that the intensity of light is one third that of the double square edge. And though internally reflected glare is still evident with the OptiEdge, the amount is less at 35 and 55 degrees than with the double-square edge," he said.
The researchers are now reviewing data on YAG rates and posterior capsule opacification among patients with the OptiEdge lens. Other studies do demonstrate that the OptiEdge does protect against opacification of the posterior capsule, he stressed.

Randall J. Olson MD commented that edge glare may not be the only important factor to consider with IOL design:
"The radius of the curvature of the implant has dramatic impact. The flatter the implant, the more glare there will be. And increasing the index of refraction will also increase glare."
His own study of 100 patients implanted with a frosted SA-30 lens and the MA-30 lens showed that patients were much more satisfied with the OptiEdge, and that glare problems were reduced with it. In one patient with intractable dysphotopsia with an SA-60 IOL exchange resolved his problem with a Sensar-E IOL.

"Frosting doesn't seem as good as the OptiEdge. Our data indicates that the Optiedge is a design that works and still allows us to have a square edge," Dr. Olson said.
Albert J. Galand, MD, questioned whether the Acrysof might be superior in keeping the margin of the anterior axis over the optic. The anterior sharp edge could have a role in keeping the anterior capsule in place instead of sliding underneath the edge of the optic, he noted.
In response, Dr Black commented that OptiEdge lenses centre very well, and, at the very least, show as little, if not less, tendency than the one-piece acrylic lenses to decentre post-operatively.

Dr. Bradley Black
drblack@eye.net
Dr. Randall Olson
John A. Moran Eye Center, Salt Lake City, Utah.
randall.olson@hsc.utah.edu

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