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September 2003
IN THIS ISSUE

New device creates alcohol-free epithelial flaps to improve healing and reduce haze


New IOL fixes suture-free in capsule-less eyes

Researchers race to produce bionic vision

Implantable telescope shows promise in AMD

New IOL Tackles Anterior-Capsule-Related Complications

Prospective study shows water jet phaco as effective as ultrasound for majority of cataracts

Laser microkeratome may reduce flap complications and improve visual outcome

Customised wavefront-guided ablation: exciting technology but beware the hype

Multifocal ablation results promising in presbyopia

In line phaco-filter aims to improve safety

Studies link genes to age-related cataract

Human genome project yielding clues to the aetiology of many ophthalmic disorders

New IOL 'adjusts' postoperatively to target refraction

Cold phaco heats up as new era dawns

Hartmann-Shack aberrometer finds new application in evaluation of nuclear cataract

Refractive surgery can improve quality of life - survey

Large retrospective study supports early intervention in paediatric cataracts

Study tracks blade influence on flap thickness

Study shows multifocal IOL implantation provides good binocular vision

Study revives hyperopic LASIK centration debate

Phakic IOL better than LASIK for high myopia

Getting to grips with ocular herpes

New rounded IOL edge design reduces glare

25-gauge vitrectomy needle speeds surgery

Indications for botulinum toxin treatment continue to expand

Experts debate value of customised ablation

FEATURES
From The Editor
Reflections on Refractive Surgery
Prime Site
Bio-ophthalmology
Eye On Travel
Collectors Eye
Regulatory Matters


Refractive surgery can improve quality of life - survey

Laszlo Dosa in Ft. Lauderdale

A quality of life survey instrument developed by British researchers that compared patients' feelings about spectacles, contact lenses and refractive surgery appears to give the edge to the latter option.
Konrad Pesudovs PhD told EuroTimes that on the 100-point Quality of Life Impact of Refractive Correction (QIRC) scale, the mean score of refractive surgery patients was 50.2. The contact lens group scored significantly lower, at 46.7, and the spectacle lens group even lower than that, at 44.1.

British researchers gave the 20-question QIRC questionnaire to 225 people -- 75 in each correction mode -- for validation and to compare performance between each of the three groups. The only restriction had to do with age. As the QIRC questionnaire was designed for non-presbyopic patients, the subjects in the study were all under 40 years of age.

"That is very important because the content of the questionnaire for presbyopic people would need to be different. Issues relating to using bifocal or reading glasses, or using multifocals for example with driving, would be quite different in terms of symptoms, functional problems, etcetera," Dr. Pesudovs noted.
He added that the necessity to confine the study to pre-presbyopes became apparent in the early stages of the development of the questionnaire when it was realized that questions for presbyopes did not fit pre-presbyopes.

The subjects for the study were drawn from 14 optometric practices and five Ultralase refractive surgery centres spread throughout the UK. The refractive surgery subjects had undergone LASIK at least three months prior to filling out the questionnaire. The groups were matched for age, gender, ethnicity and socio-economic status and were representative of the overall UK population seeking eye care.

Quality of lifestyle
Those who had undergone refractive surgery had significantly better quality of life scores compared to contact lens wearers and spectacle wearers. Moreover, the advantages of refractive surgery appeared to be especially pronounced with regard to several specific aspects of quality of life.

For example, the refractive surgery group had a markedly better score than contact lens wearers with regard to "eyes feeling tired or strained" (50.25 vs 44.21) and "seeing on waking"(50.98 vs 42.42). In addition, with regard to the item "How concerned are you about your vision being not as good as it could be" the difference in scores was highly significant in favour of refractive surgery patients, who had a score of 54.42. That compared to 45.90 for the contact lens group and 42.19 for the spectacle wearers.
In general, spectacle wearers fared poorly on psychosocial well-being items. However, they had better scores than the other two groups regarding "concerns about medical complications."

Furthermore, a small proportion (6.7%) of the refractive surgery participants had a very low quality of life score (37.9 + 2.1) due to post-operative complications such as dry eye and residual refractive error.
Dr Pesudovs said he believes that the use of Rasch analysis demonstrates the QIRC questionnaire provides a valid measure of quality of life in refractive correction. The overall outcome suggests that people with refractive correction experience good quality of life regardless of correction type, but correction preference is probably driven by individual variations as related to quality of life issues.

He added that the questionnaire could be used in ophthalmic outcomes research in general. It would be applicable to any research on spectacle wearers, any research on contact lens wearers, and any research on refractive surgery. It would be particularly suitable for the pre- and post-operative study of refractive surgery.
Dr Pesudovs presented his results in a poster presentation at the annual meeting of the Association for Research in Vision and Ophthalmology.

Konrad Pesudovs, PhD
University of Bradford, Bradford, UK
konrad@pesudovs.com

 

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