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One line of regained visual acuity
is a snip at just €120
By
Stefanie Petrou-Binder MD
NUERNBERG - The €120 cost to the insurer of one line of regained
visual acuity is good value considering the significant associated
improvements in patients'quality of life, according to an investigation
carried out at Mainz University, Germany.
Why figure out what one line of regained visual acuity costs? At
this year's Congress of German Ophthalmic Surgeons, Frank Krummenauer
MD, DSc and colleagues explained that for an accurate cost evaluation
of cataract surgery, the patient's subjective and objective visual
acuity improvements must be seen relative to the direct expenses
carried by the insurer.
The researchers determined that each gained line of visual acuity
resulting from cataract surgery effectively costs the health insurer
E120.
With visual acuity improvements that have been attained at up to
five lines per operated eye, the obvious cost effectiveness of cataract
surgery is a relevant aspect to consider in light of patient satisfaction
associated with regained vision.
In addition, it represents a straight argument in reimbursement
discussions with insurers.
The investigation was carried out by the Mainz University's Co-ordination
Centre for Clinical Trials (KKS) and its goal was to evaluate cataract
surgery from an economic viewpoint.
As most studies consider only the number of visual acuity lines
gained following cataract surgery - the functional measurable improvement
- the authors considered it valid as a surrogate endpoint for patient
satisfaction and objective clinical outcome in an assessment of
cost effectiveness.
However, they pointed out that additional cost effectiveness correction
for quality of life data was performed.
Since the gain in visual acuity substantially correlates with the
major determinants of quality of life and cataract patients' satisfaction,
this correction did not significantly change the overall findings.
The team used the visual acuity improvement obtained in patients
operated on as an input parameter to quantify the expense entailed
per line of gained acuity.
As each gained line represents an incremental rise in patient satisfaction
and in the quality of life of the patient, the authors sought to
estimate the value of the "individual visual acuity line".
To obtain the necessary data, the authors carried out a meta-analysis
on the efficacy of cataract surgery based on monofocal IOL implantation
beginning in 1991 and including clinical trials until 2001.
They studied online ophthalmic surgical sources, principally Medline
and PubMed, using key words such as "cataract and quality of
life", "cataract and benefit", "cataract and
effectiveness", and "cataract and patient satisfaction"
to amass input data.
Meta-analysis
Included in this meta-analysis were prospective randomised trials
involving at least 40 patients per therapy arm.
The net expense carried by the insurance companies was estimated
to be approximately €600 per patient operated on in hospital
within the chosen 10-year time frame, including patient-associated
care expenses and material costs.
The overall cost estimates were provided by Burkhard Dick MD, Department
of Refractive Surgery, University of Mainz Eye Hospital, Mainz,
Germany.
Annette Lohmeier MD included 25 clinical trials in their meta-analysis
which fulfilled their confirmatory set of criteria. The poster displayed
three criteria typical of these studies.
One example study showed a median increase in visual acuity from
20/100 to 20/33 within two months after surgery with 99% of these
patients reporting satisfaction with the treatment and 88% with
their visual results.
A second one showed visual acuity improvements of less than or equal
to 20/30 in 80% of patients one month following surgery.
Finally, one of the studies introduced to the meta-analysis showed
a visual acuity improvement from less than 20/200 to greater than
or equal to 20/60 in 15% of patients without correction and in 38%
of the same patient group with correction.
The overall meta-analysis revealed a median visual acuity improvement
of five lines; as cataract surgery/care roughly costs the insurer
E600 during the time range of the analysis, the value of one gained
line is approximately E120.
Dr Krummenauer and Dr Lohmeier emphasised that, although their meta-analysis
could not be comprehensive because of publication bias and the quite
specific inclusion criteria involving both effectiveness and outcome
quality, the estimated cost per visual acuity line at least offers
an interesting viewpoint for further discussion and prospective
analysis.
They added that further studies must focus on patient satisfaction
and improved quality of life as a vital aspect of cataract surgery,
in addition to the objective clinical goal of improving visual acuity.
"However, the cost effectiveness of cataract surgery can, at
least in a first surrogate analysis step, be estimated by evaluating
the incremental improvement of visual acuity per gained line in
comparison to the expenses the insurer carries corrected for the
self-reported gain in patient satisfaction and quality of life.
The latter can be assessed by means of psychometric analysis,"
Dr Krummenauer said.
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