ESCRS Homepage

November 2002
IN THIS ISSUE

Wavefront seeks a higher order of vision correction


New laser system for intraoperative measurement of LASIK flap thickness

Visual prostheses use neurotransmitter retinal chips to stimulate retinal function

Wavefront emerges as powerful tool for night vision

Allegretto promising for hyperopia and hyperopic astigmatism

Topography's role in wavefront systems

IOP measurement after LASIK may be unreliable

LASEK may only play support on refractive stage

Solid-state laser PRK yields favourable results for myopia

GTS-assisted DLK useful alternative to PK for keratoconus

Glaucoma common after PK bodes poorly for visual outcome

Classic drawbacks of PRK succumb to new strategies

New insight into LASIK dry eye pathogenesis

Use of anti-inflammatories after capsulotomy questioned

Good quality training leads to good quality cataract surgery

One line of regained visual acuity is a snip at just €120

Mitomycin-C provides effective haze prophylaxis

Long-term concerns linger on safety of Mitomycin-C

German politicos promise health reforms

Honey forms biblical basis for corneal oedema

Routine two-step LASIK after PK unnecessary

Plasma knife provides clean and accurate cut for capsulorhexis

Glaucoma therapy targets apoptosis and trabecular meshwork

Viscocanalostomy viable choice for cataract-glaucoma

Device allows needle-free injections into smallest vessels

New river blindness therapy may provide panacea for 18m people

Daytime running lights may soon be compulsory in all EU states

Intracorneal lamellar implants still a questionable option

Aqualase system viable for small incision cataract removal

Unilateral von-Hippel disease with optic nerve head

FEATURES
From The Editor
Reflections on Refractive Surgery
In Your Good Books
An Eye On Travel
Bio-ophthalmology
Outlook on Industry
Regulatory Matters



New laser system for intraoperative measurement of LASIK flap thickness

By Roibeard O'hÉineacháin

NICE - A new laser imaging system may provide more accurate corneal pachymetry than ultrasound instruments and allow for the intraoperative measurement of LASIK flap thickness.

The new system uses triangulation between a laser and a high-resolution digital camera to create a three-dimensional map of the entire corneal surface, instead of just one point as in ultrasound pachymetry, an Italian specialist told told the XX ESCRS Congress.

Moreover, the system could be mounted onto an excimer laser system and provide data to guide ablation patterns, Francesco Carones MD said.

"Microkeratomes may produce unpredictable flap thicknesses which can in turn lead to inadequate residual stromal thickness and an increased risk of ectasia. That is why there is a need for intraoperative pachymetry.

"However, ultrasound pachymetry only measures single points as regards the thickness and there can be difficulty in finding the thinnest corneal point and the center of ablation. The intraoperative corneal topographer was designed to address these issues," he explained.

The system works by using an ultraviolet 193 nm laser source to project a grid or pattern of light that reaches the cornea where it causes the surface to fluoresce. A high-resolution digital camera detects the pattern.

A 30° angle between laser and camera provides the triangulation necessary to interpret the distortions in the laser pattern as a 3D representation of the cornea's contours.
The laser pattern consists of approximately 100 lines with line width of 50 microns and 10 line-pairs/mm on the central cornea.

"When the fringes are projected on a plane there is no distortion and the lines are straight up and down. However, on a surface like the cornea the lines assume a curvature with a difference in dimension that is proportional to the contour of the surface.

"To obtain a flap thickness measurement, the surgeon has merely to measure the difference in the fringe pattern of the cornea before and after flap creation," he said.
In a small trial to evaluate the accuracy of the instrument, Dr Carones and his associates used the ICT instrument to measure the corneal thickness in six LASIK patients before and after flap creation with an SKBM microkeratome.

The microkeratome was set to cut flaps 150 microns in thickness.
However, measurements with the ICT showed that the thickness of LASIK was much greater (above 200 microns) in the region where the microkeratome blade enters the cornea.

In fact, the nominal thickness was only achieved in the 6.0 mm diameter central area of the flap.

Dr Carones emphasised that the ICT Corneal Topographer is at present only an investigational instrument and its accuracy remains to be proved.
Moreover, its registration and calibration will need improvement before it is ready for clinical use. But when fully implemented the technology could enhance the precision of refractive surgery.

"The accuracy of the instrument seems to be quite consistent and gives enough information to measure surface regularity, particularly with regard to the correction of higher order aberrations.

"This technology could therefore be integrated into a laser system in order to guide the laser for custom ablation," he noted.

Top