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August 2003
IN THIS ISSUE

Verteporfin’s efficacy in AMD comes into focus


Symposium to explore hyperopia treatment options

Epikeratophakia for keratoconus gets a second look

AMD UPDATE

Cancer trials give anti-angiogenesis a boost

RhuFab V2 trials show positive results in AMD

PDT trials aim to refine AMD treatment indications

Studies shed light on lutein’s importance to vision

Watchful eye and good use of preventive strategies needed to limit risk of phaco burn

Prolate lens design improves contrast sensitvity

German ophthalmologists prefer acrylic IOLs despite wider range of PMMA implants available

Square-edged IOL tackles PCO problems

New IOL injector yields optimum implantation with reduced learning curve

New anterior chamber phakic IOL shows good longterm safety and predictability in high myopia

Topographically guided LASIK proves first line treatment for decentred ablations

Customised ablation research produces
some answers but raises even more questions

Phakic IOL may help in refractory amblyopia

Customised approach useful in resolving
decentred ablations after LASIK and PRK

Screening can prevent post-op binocular disturbances

Anticonvulsant joins list of agents implicated in acute angle-closure glaucoma

New study shows surprise link between
hyperglycaemia and retinopathy of prematurity

Waiting lists put melanoma patients at risk

Tropicamide has little impact on higher order aberrations in myopes undergoing wavefront analysis

Swedish team tackle Moken mystery

FEATURES
From The Editor
Reflections on Refractive Surgery
Bio-Ophthalmology
Bio-ophthalmology
Eye On Travel
Regulatory Matters


German ophthalmologists prefer acrylic IOLs despite wider range of PMMA implants available

Stefanie Petrou-Binder MD
in Nuernberg, Germany
Jörn Kuchenbecker MD

NEW studies of cataract surgery in Germany paint a picture of a market in transition. It seems that while German surgeons have more PMMA types of IOLs to choose from than any other kind, they nonetheless prefer to implant acrylic lenses, according to reports at the annual Congress of the German Ophthalmic Surgeons (DOC).

Jörn Kuchenbecker MD reviewed the findings from an online database he created (www.iol-info.com) which tracks surgeon choices in a presentation entitled ‘The German IOL Report 2003’. The web site lists the entire spectrum of intraocular implants available for anterior segment surgery in Germany today.

"Our analysis showed that PMMA posterior chamber IOLs are still available in the highest number in Germany, followed by one-piece acrylic posterior chamber IOLs," Dr Kuchenbecker noted.

Dr Kuchenbecker evaluated data which included 587 intraocular implants from a total of 24 different providers in Germany. The site provides information on each IOL in terms of manufacturer (including name, address, email, phone, fax and home page), lens type, optic material, haptic material, A constant, and ACD (ultrasound), as well as additional technical data (diameter, haptic angle, refractive index).

Of the 587 implants he assessed, nearly 76% were posterior chamber lenses. Close to 8% of the total number of available IOLs were anterior chamber lenses and 6% were capsular tension rings. Another 3% to 4% of implants were phakic IOLs, while the remaining 6% included a variety of implants.

A total of 94% of posterior chamber lenses available to German ophthalmic surgeons were conventional types. Between 3% and 4% of posterior chamber lenses were for aniridia, 1% were toric and just under 1% were anti-diplopia devices.
Some 60% of posterior chamber lens optics listed on the database were made of PMMA, with another 20% of optics were made of acrylic materials. Another 10% of available posterior chamber optics were made of silicone. A small percentage of optics, less than 1%, were made of hydroxy-ethyl-met-acrylate (HEMA), he reported.

A majority (63%) of the acrylic posterior chamber lenses had acrylic haptics. Another 12% had PMMA haptics, 5% had polyvinyl-fluoride (PVF) haptics and a little less than 3% had prolene haptics. The majority of silicone optic IOLs had PMMA haptics. A few of this type of lens had haptics made of silicone, PVF or polyamide.

Dr Kuchenbecker pointed out, however, that the types and numbers of IOLs available to German ophthalmic surgeons represented in his study do not necessarily reflect actual surgical practices.

According to the latest DGII/BVA survey (German-speaking Association for Intraocular Lens Implantation and Refractive Surgery/Professional Association of Ophthalmologists), and in strong contrast to the data reported by Dr Kuchenbecker, ophthalmic surgeons are implanting less than 20% PMMA posterior chamber IOLs.

Seb Ober MD reported the outcome of the survey at the DOC Congress in Nuernberg. The DGII survey is based on the responses of 280 German ophthalmic surgeons to a surgical preferences and practices questionnaire.

He revealed that the German ophthalmic surgeons choice of lens material is hydrophobic acrylic lens material. Surgeons operating in outpatient clinics implanted hydrophobic acrylic IOLs in roughly 41% of cases. The survey results vary slightly between surgeries carried out in outpatient clinics, office surgical units and hospital or private surgical units with reserved beds.

According to the survey, hydrophilic acrylic IOLs represented another 26% of lenses implanted in German ambulatory clinics and silicone lens material represented 18%. Ophthalmic surgeons opted for PMMA lens material in only around 15% of cases.
Dr Ober’s presentation of the 2003 survey showed that the current figures differ greatly from the DGII statistics accrued in 1998, when acrylic lenses made up only around 20% of the lenses implanted by ophthalmic surgeons, while they chose PMMA lenses, by contrast, in over 60% of cases.

Dr Kuchenbecker predicts that the shift in the current surgical practice will soon also become evident in the types and numbers of lenses available to surgeons. He said the web site (IOL-info.com) updates changes as they come about, as well as featuring articles on the latest lenses and related subjects.

The site also offers helpful links to IOL-related sites, major English and German-language journals and ophthalmological associations. It even offers an email newsletter for interested parties.

An IOL databank is a good place for ophthalmic surgeons to turn to when looking for an IOL to meet their personal needs and specifications. It also provides a much-needed overview in light of the myriad IOLs offered and also serves as an update for anyone interested in the current IOL market, Dr Kuchenbecker said.

An English-language databank is available to surgeons at www.docholladay.com/search.cfm. Created by Jack Holladay MD, that site allows the user to search across numerous parameters including manufacturer, lens type and optic material.

Jörn Kuchenbecker MD
Otto-von-Geuricke University, Magdeburg, Germany
mail@jkuchenbecker.de

Seb Ober MD
Seb.ober@t-online.de

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