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August 2002
IN THIS ISSUE

French specialists in conflict with Government as crisis looms


PRK gets a second look for poor LASIK candidates

Therapeutic apheresis slows the downhill course of dry AMD

Zyoptix ablation refinement uses two-step approach to achieve best visual results

Survey shows PRK is more widely practised
than LASIK in treatment of myopia in France

Flap hinge position no effect on corneal sensitivity

LASIK nomograms hide corneal biomechanical and epithelial profile changes induced by surgery

High-tech treatment for irregular astigmatism

Avoiding cataract surprises after refractive surgery

Antioxidants mitigate cataract risk and progression

Times are set to change for German eye surgeons

Study reveals next day follow-up visit may
be unnecessary for most cataract patients

High water content hydrophilic acrylic IOL gets the blues

Careful evaluation for diabetics with cataracts

Phaco does not worsen diabetic retinopathy

Night light might shade diabetic retinopathy

Diabetes debate continues

Common cardio drugs may improve PDT outcomes

Researchers say EBRT shows new promise for treatment of eyes with subfoveal CNV

FEATURES
From The Editor
Reflections on Refractive Surgery
Healthcare In Europe
Bio-ophthalmology



Study reveals next day follow-up visit may be unnecessary for most cataract patients

By Cheryl Guttman

Fort Lauderdale - Skipping the traditional follow-up visit the day after surgery does not adversely affect the outcomes of patients undergoing uncomplicated phacoemulsification surgery, according to a new prospective randomised study.

Researchers from Musgrove Park Hospital, Taunton, UK, evaluated outcomes for 188 patients randomised to same day discharge (SDD) with a first follow-up visit scheduled at two weeks postoperatively and 174 patients assigned to next day review (NDR) with the second planned follow-up after two weeks.

In the NDR group, 21 (12%) patients received altered management at day one with oral acetazolamide treatment for raised IOP being the most common intervention (n=14, 8%). Other complications included marked corneal oedema and uveitis, each occurring in two eyes. One patient had a wound leak, another had exposure requiring treatment and one had a loose suture removed.

Twelve extra visits occurred prior to the 2-week visit, primarily for symptoms related to eyedrop use or for IOP follow-up.

In the SDD group, there were seven extra visits prior to the second week follow-up, including three for patient reassurance. Iris prolapse detected in a single eye was the only potentially serious complication noted at the two-week visit, but it did not require surgical intervention or result in poor acuity.

Stratified randomisation

Randomisation was stratified according to whether patients were having first or second eye surgery. Patients in the SDD group had their eye pads removed two to three hours after surgery and received discharge counseling and medication. Patients in the NDR group went home with the eye padded and returned the next morning for slit lamp review.

The exclusion criteria eliminated patients with a single sighted eye, those undergoing concomitant surgical procedures, categorised as ASA Grade III or worse, or those deemed to have insufficient social support to be cared for overnight at home.

The protocol allowed the surgeon or anaesthetist to override patient allocation; 13 SDD patients were assigned to return for next-day review and one NDR patient was seen for initial follow-up on the day of surgery. Four of the 13 SDD patients required an alteration in standard management at the Day 1 visit for either elevated IOP or corneal oedema.

Researchers noted no significant differences in objective and subjective visual outcomes. Snellen visual acuity of 20/40 or better was present in 83% of eyes in both groups at week two, reported Christopher Tinley MB, ChB, at this year's meeting of the Association for Research in Vision and Ophthalmology.

Responses to the Vision Core Module 1 (VCM-1) questionnaire, which was mailed four months after surgery, showed approximately 70% of patients in both groups had scores less than 1.0, indicating none or little concern about vision.

"Any conditions which may have been present in our SDD group on the first day after surgery did not result in detectable adverse consequences, despite going untreated.
"However, we estimate that eliminating the traditional Day 1 postoperative visit in patients having routine phacoemulsification surgery would save approximately 1,000 visits for eligible patients going through our department in the six month recruitment period. That practice, therefore, has significant cost- and labour-saving advantages without compromising patient safety or visual outcomes," Dr Tinley said.

He noted that previous papers on this topic, consisting of retrospective studies and prospective, nonrandomised trials, report complication rates of 3% to 41% among patients seen on the first day after phacoemulsification.

The authors of those various articles suggest the main reasons for scheduling a next-day review are that it provides the opportunity to treat raised IOP and detect early, potentially sight-threatening complications, such as iris prolapse.

Long-term visual function
"There is no current evidence, however, that treating transient postoperative IOP spikes influences long-term visual function. In addition, there were no cases of iris prolapse seen on day one in the NDR group in our study population and of two cases that occurred in the SDD group, one was anticipated in a patient having complicated surgery and was not detected until day three despite earlier follow-up.

"The second case of iris prolapse may or may not have been present on day one," Dr Tinley explained.

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