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Photorefractive keratectomy concurrent with accelerated cross-linking: safety and efficacy outcomes at 6 months

Poster Details

First Author: J.Reyes SPAIN

Co Author(s):    F. Duch   M. Marti   R. Escude   M. Crapanzano           

Abstract Details


To assess the safety and efficacy of Photorefractive keratectomy (PRK) applied concurrently with Accelerated Crosslinking (CXL-a) in a group of miopic patients.


Refractive Surgery Department,Institut CatalĂ  de Retina(ICR), Barcelona, Spain


Interventional case series at Refractive Surgery Department of Institut CatalĂ  de Retina, Barcelona. Between June and December of 2014, a group of 10 patiens had PRK with concurrent CXL-a for treatment of myopia. The follow-up is 6 months by now. The primary inclusion criteria were bilateral myopia or myopia with astigmatism, age older than 18 years, a BCVA of 20/20, and stable refraction. Corneal topography with no criteria of subtle keratoconus was also required. The attempted correction ranged from -1.25 to -5.75 diopters (D). Patients were examined preoperatively, 1, 3, 6, months postoperatively.


A total of 19 eyes of 10 patients were enrolled, with a mean age of 30.36 years. The mean preoperative spherical equivalent was -3,74D. The mean preoperative UCVA was 0.07 and the BCVA 1.0. The preoperative BFSp/BFSa (Efkarpides) ratio was 1.21 (normal) and the mean differential display Belin Ambrosio 0.67. At 1-month follow-up the visual acuity values were 0.83 and 0.98 respectively. At the 3-month follow-up, values of UCVA and BCVA improved to 0.96 to 1.04. No eye lost 1 or more lines of CDVA at the final visit. Data collection corresponding to the 6-month follow-up is being conducte.


While CXL was designed for the treatment of keratoconus and ectasia, the use of PRK with concurrent CXL-a could help reduced the rate of regression of the treated ametropias. A new method to stabilize the patient's refraction and the cornea after refractive surgery would be very useful.

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