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Visual performance simulation of a novel presbyopia-correcting IOL

Poster Details

First Author: Y.Liu USA

Co Author(s):    C. Rich   S. Lee   M. Choi   S. Lee           

Abstract Details

Purpose:

To evaluate the laboratory bench simulation of the Contrast Sensitivity (CS) and Visual Acuity (VA) differences between a novel presbyopia-correcting intraocular lens and the AcrySof IQ ReSTOR +3D multifocal intraocular lens for simulated object distances from infinity to near.

Setting:

Experimental study conducted at Alcon Laboratories, Fort Worth, Texas, USA

Methods:

Laboratory MTF measurement of bench model eyes was performed with the novel Presbyopia-Correcting IOL (Lens 1) and ReSTOR +3D multifocal IOL (Lens 2) respectively. CS difference between the two lens models was evaluated with the measurement results. Badal images of a letter chart at simulated object distances from -1.0 D to +3.0 D at every 0.25D increment were recorded and post processed with a neural network algorithm to estimate the VA of the two lenses. Neural network training was accomplished using four sets of clinical defocus VA databases from commercially available IOLs.

Results:

Distance CS reductions of Lens 1 relative to Lens 2 were -0.066±0.009 log units at 3 cpd, -0.096±0.010 at 6 cpd, -0.127±0.009 at 12 cpd, and -0.120±0.013 at 18 cpd. Near CS reductions were -0.142±0.023 log units at 3 cpd , -0.003±0.020 at 6 cpd, -0.063±0.024 at 12 cpd, and -0.006±0.021 at 18 cpd. The visual acuities obtained for Lens 1 were -0.034 LogMAR at distance, 0.112 at 80cm, 0.069 at 70cm, 0.018 at 60cm, -0.001 at 50cm, and 0.017 at 40cm respectively. The corresponding VA values for Lens 2 were -0.047, 0.201, 0.184, 0.138, 0.066, and 0.044 LogMAR respectively.

Conclusions:

The novel presbyopia-correcting IOL can provide equivalent distance and near performances in visual acuity and contrast sensitivity compared with the multifocal ReSTOR +3D lens. The intermediate performance of the novel presbyopia-correcting IOL is superior to the multifocal lens and it can potentially offer VA improvement of about -0.078 LogMAR at 80cm, -0.115 LogMAR at 70 cm, and -0.121 LogMAR at 60cm. With a one line difference in visual acuity on the Snellen VA chart equal to approximately 0.1 logMAR these results indicate more than a 1 line improvement for the novel presbyopia-correcting IOL at 70cm and 60cm.

Financial Disclosure:

One or more of the authors is employed by a for-profit company with an interest in the subject of the presentation

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