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The role of ophthalmologists for early diagnosis of Kawasaki disease

Poster Details

First Author: S.Kim SOUTH KOREA

Co Author(s):    S. Kim   M. Kim                 

Abstract Details

Purpose:

To identify ophthalmologic features of Kawasaki disease(KD), and to develop criteria for early diagnosis of atypical KD patients.

Setting:

Department of Ophthalmology, The Catholic University of Korea Uijeongbu St. Mary’s Hospital, Korea Between October 2013 and January 2015, All patients suspected of KD refered to department of Ophthalmology for evaluation of anterior uveitis were reviewed retrospectively.

Methods:

A retrospective chart review of 60 consecutive patients with suspected of KD seen. This diagnostic criteria for atypical KD is the clinical symptoms which fulfilled four out of six diagnostic criteria below of typical KD with or without the presence of coronary artery changes, and were inconsistent under a through clinical investigation with any other illness similar to Kawasaki disease.

Results:

Among a total of 60 patients, 14(23.3%) were diagnosed as other febrile disease, 32(69.6%) were typical KD, 14(30.4%) were atypical KD. All patients with anterior uveitis were diagnosed as KD (25 in typical KD, 7 in atypical KD, the positive predictive value calculated was 100%). 69.6% (32/46) of the prospectively studied children with KD demonstrated anterior uveitis(The sensitivity was 69.6% and The specificity was 50%). The average anterior chamber cell grading(SUN) was 1.3. Transient bulbar conjunctival injection was present in 100% of the KD cases. The anterior uveitis fully resolved after the onset of disease in all patients.

Conclusions:

KD may occur in atypical type, ranging over many severe involvements of vital organs including the coronary artery. Because late diagnosis of KD increases the risk for coronary artery abnormalities, although the follow-up of all KD cases suggests that the uveitis is probably self-limited, slit-lamp examination should be useful in the evaluation of patients with suspected KD. Therefore, ophthalmologists can play an important role for early diagnosis of KD.

Financial Disclosure:

NONE

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