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The Ex-PRESS glaucoma shunt vs non-penetrant deep sclerectomy in open-angle glaucoma: a prospective randomized study and preliminary results

Poster Details

First Author: M.Munoz SPAIN

Co Author(s):    A. Anton   M. Castany   A. Martinez   J. Urcelay   J. Moreno   F. Munoz Negrete     

Abstract Details


Express shunt device and deep sclerectomy have been evaluated previously and even when both procedures are effective in reducing intraocular pressure, there are no comparative studies between them. We performed a prospective, multicenter, randomized trial to evaluate efficacy and safety of combined cataract and filtering surgery with Ex-Press implant versus deep sclerectomy (NPDS) in 12 months follow up.


Parc de Salut Mar and Hosp. Vall d'Hebron Barcelona, Hospital Gregorio Marañon and Hospital Ramon y Cajal Madrid, Clínica Universitaria Navarra, Hospital San Eloy Bilbao.


This was a prospective, randomized trial. Eyes from enrolled patients were randomly assigned to either Ex-PRESS implantation under a scleral flap, or trabeculectomy. The main outcome measures were: mean intraocular pressure (IOP), postoperative medication use, visual acuity, and incidence of complications. Complete success was defined as an IOP of 4 mmHg and 4 mmHg and


There were 78 patients (80 eyes) with primary open-angle, pseudoexfoliative, or pigmentary glaucoma enrolled in the study. A total of 84.6% of patients receiving Ex-PRESS and 60.0% of patients receiving trabeculectomy (P=0.0230) achieved complete success. The respective proportions of patients achieving an IOP >4 mmHg and


In open-angle glaucoma, the Ex-PRESS mini glaucoma shunt implanted under a superficial scleral flap produces significantly higher success rates, and a similar complication rate, compared with trabeculectomy. The Ex-PRESS is a safe and effective device for treating open-angle glaucoma.

Financial Disclosure:

One or more of the authors research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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