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Tolerance and the target intraocular pressure in primary open-angle glaucoma

Poster Details

First Author: A.Chava RUSSIA

Co Author(s):    S. Balalin   V. Fokin                 

Abstract Details

Purpose:

To study whether age, blood pressure, glaucoma stage, corneal thickness and anterior-posterior ocular globe size have impact on the level of target pressure in patients with primary open-angle glaucoma viewed from a perspective of tolerant pressure.

Setting:

There were examined 1310 patients (1638 eyes) with primary open-angle glaucoma and 365 healthy persons (640 eyes).

Methods:

We studied relationship between tolerant intraocular pressure and target pressure with consideration to risk factors of glaucoma progression.

Results:

Mean value of true tolerant IOP in glaucoma patients equaled 16,5±0,1 mm Hg, which exceeds mean value of individual pressure in healthy persons by 2,5 mm Hg (P<0,001). Target pressure should also be tolerant pressure below 2.5 mmHg (P<0,05). Multivariative analysis made in possible to find the relationship between tolerant IOP, patient’s age, diastolic blood pressure, central corneal thickness (CCT), anterior-posterior ocular globe size (APS) in patients with initial glaucoma stage. Primary open-angle glaucoma progression induced decrease of tolerant pressure: on average by 0,3 mm Hg with every primary open-angle glaucoma stage.

Conclusions:

Decrease of tolerant IOP in patients with primary open-angle glaucoma is registered in dependence with patient’s ageing, growth of anterior-posterior ocular globe size (APS), lowering of blood pressure, decrement of central corneal thickness and glaucoma progression.

Financial Disclosure:

NONE

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