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Sliding keratoplasty followed by transepithelial iontophoresis collagen cross-linking for pellucid marginal degeneration

Poster Details

First Author: L.Spadea ITALY

Co Author(s):    G. Maraone                    

Abstract Details


To describe the changes in visual acuity and in topographic analysis in a patient affected by pellucid marginal degeneration (PMD)submitted in one eye to sliding keratoplasty and three months later to transepithelial iontophoresis collagen cross-linking (I-CXL).


Eye Clinic, “A. Fiorini” Hospital, Sapienza University of Rome, Terracina (Latina), Italy


A 59 year old woman with bilateral PMD, more advanced in the left eye, contact lens intolerant, was treated by sliding keratoplasty before and 3 months later to transepithelial iontophoresis collagen cross-linking in left eye.


After one year of follow-up the corrected visual acuity increase from 20/200 to 20/50, and the videokeratographic patterns significatively improved.


Sliding keratoplasty combined with I-CXL treatment were shown to be safe and effective in the treatment of advanced PMD. The patient described an improved and comfortable quality of vision and described herself as being satisfied with the outcome.

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