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Corneal cross-linking for corneal deformation caused by eye picking in patients with Tourette syndrome

Poster Details

First Author: M.Shinzawa JAPAN

Co Author(s):    N. Kato   K. Kasai   J. Shimazaki              

Abstract Details


Tourette syndrome (TS) is a neuropsychiatric disorder characterized primarily by multiple motor tics. Eye tics are well known as early manifestations of TS. We report on the effectiveness of corneal crosslinking (CXL) for corneal deformation presumably caused by eye picking in a patient with TS.


Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan


A 24-year-old man diagnosed with TS was referred to us due to deterioration in his right eye vision in June 2010. Visual acuity was 20/50 OD and 20/20 OS, steepest keratometric value 56.6D OD and 45.4D OS, and central corneal thickness was 451 μm OD and 429 μm OS. Corneal tomography on both eyes showed corneal deformation with strong irregular astigmatism. Despite medication, he continued to pick his eyes and his ectasia gradually progressed during the 3 year follow-up period. Corneal thinning became remarkable on his right eye, and he underwent CXL on his right eye in August 2013.


At 15 months after CXL on his right eye, his visual acuity was 20/63 OD and 20/63 OS, the steepest keratometric value was 55.9D OD and 47.5D OS. The corneal tomography showed no signs of ectasia progression on his right eye. After CXL on his right eye, he increased the picking of his left eye and the ectasia in his left eye progressed.


In this case, CXL was effective in preventing the progression of corneal deformation due to eye picking.

Financial Disclosure:

One or more of the authors receives non-monetary benefits from a company producing, developing or supplying the product or procedure presented.

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