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Corneal demarcation line depth with different accelerated collagen cross-linking protocols

Poster Details

First Author: A.Sherif EGYPT

Co Author(s):    A. Osman                    

Abstract Details

Purpose:

To compare the depth of demarcation line measured by anterior segment OCT one month after collagen cross0linking using different ultraviolet intensities for the management of progressive keratoconus.

Setting:

Rowad Cornea Center, Giza,Egypt Dar Oyoun eye hospital, Giza ,Egypt

Methods:

Prospective , Comparative and Clinical study, 30 eyes divided randomly into 3 groups: Group A: 10 eyes underwent CXL using 9Mw/cm2 UVA for 10 minutes Group B: 10 eyes underwent CXL using 18mW/cm2 for 5 minutes Group C: 10 eyes underwent CXL using 30mW/cm2 for 4 minutes In all cases, the epithelium was removed before riboflavin application. In all cases, Vibex Rapid (0.1% riboflavin & hydroxyl propoxy methyl cellulose ) was used for 10 minutes before UV application. 1 month after surgery all cases were photographed using Optovue anterior segment OCT (Optovue Inc, CA)and the depth of demarcation line was assessed.

Results:

In all cases, the demarcation line could be elicited with Anterior segment OCT one month after surgery. The mean demarcation line depth was 293± 42 , 279±31 and 261±27µm for groups A,B and C respectively. There were no statistically significant differences between the 3 groups. Conclusion: Accelerated collagen cross-linking using various UVA intensities is associated with comparable demarcation line depths.

Conclusions:

Accelerated collagen cross-linking using various UVA intensities in keratoconus is associated with comparable demarcation line depths.

Financial Disclosure:

NONE

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