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Accelerated (18 mW/cm2) corneal cross-linking for progressive keratoconus: 18 month outcomes

Poster Details

First Author: E.Ozgurhan TURKEY

Co Author(s):    T. Kurt   Y. Yildirim   Z. Gunaydin   E. Bozkurt           

Abstract Details

Purpose:

The aim of this study was to report the outcomes of accelerated (18 mW/cm2) cross-linking (CXL) in patients with progressive keratoconus.

Setting:

Beyoglu Eye Training and Research Hospital, Refractive surgery department

Methods:

Thirty eyes of 28 patients with progressive keratoconus were included in the study. All patients underwent accelerated CXL (irradiance of 18 mW/cm2, five minutes with a total surface dose of 5.4 J/cm2). Mean outcome measures were flat keratometry (K1), step kerafometry (K2), apex keratometry (Kapex) and thinnest corneal thickness (TCT). The efficacy and safety of procedure were assessed during 18-month follow-up.

Results:

The mean age of the 11 women and 17 men was 23.76 ± 4.35 years (range 17 to 32 years). At the last visit, the K1 decreased from the baseline of 46.02 ± 2.56 D to 45.65 ± 2.65 D, the K2 decreased from 50.12±3.52 D to 49.78 ± 3.56 D, and the Kapex decreased from 56.72 ± 5.88 to 55.34 ± 5.76 D (P = 0.006, P = 0.008, P = 0.001, respectively). The TCT was 442.76±38.35µm preoperatively while it was 447.67±40.36 at 18 months postoperatively (p=0,216).

Conclusions:

The results of this study revealed that accelerated CXL (18-mW/cm2) halted the keratoconus progression without relevant side effects in patients with progressive keratoconus during 18-month follow up.

Financial Disclosure:

NONE

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