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Accelerated (18 mW/cm2) corneal cross-linking for progressive keratoconus: 18 month outcomes

Poster Details

First Author: E.Ozgurhan TURKEY

Co Author(s):    T. Kurt   Y. Yildirim   Z. Gunaydin   E. Bozkurt           

Abstract Details


The aim of this study was to report the outcomes of accelerated (18 mW/cm2) cross-linking (CXL) in patients with progressive keratoconus.


Beyoglu Eye Training and Research Hospital, Refractive surgery department


Thirty eyes of 28 patients with progressive keratoconus were included in the study. All patients underwent accelerated CXL (irradiance of 18 mW/cm2, five minutes with a total surface dose of 5.4 J/cm2). Mean outcome measures were flat keratometry (K1), step kerafometry (K2), apex keratometry (Kapex) and thinnest corneal thickness (TCT). The efficacy and safety of procedure were assessed during 18-month follow-up.


The mean age of the 11 women and 17 men was 23.76 ± 4.35 years (range 17 to 32 years). At the last visit, the K1 decreased from the baseline of 46.02 ± 2.56 D to 45.65 ± 2.65 D, the K2 decreased from 50.12±3.52 D to 49.78 ± 3.56 D, and the Kapex decreased from 56.72 ± 5.88 to 55.34 ± 5.76 D (P = 0.006, P = 0.008, P = 0.001, respectively). The TCT was 442.76±38.35µm preoperatively while it was 447.67±40.36 at 18 months postoperatively (p=0,216).


The results of this study revealed that accelerated CXL (18-mW/cm2) halted the keratoconus progression without relevant side effects in patients with progressive keratoconus during 18-month follow up.

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