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Recurrent herpetic ulcer after cross-linking

Poster Details

First Author: E.Escobar Martín SPAIN

Co Author(s):    I. Villarejo Diaz-Maroto   M. Matilla Rodero   N. Kim   L. Martin Perez   L. Modamio Gardeta   A. Arias Puente     

Abstract Details


To present a patient who received cross-linking with recurrent herpetic ulcers and stromal scars as adverse effect.


Hospital Universitario Fundación de Alcorcón


This case report is about a 39 years old women, with personal background of ocular herpes on the left eye that received a cross-linking treatment in both eyes in other centre a year before, previous to Lasik surgery that was never performed The patients complaint about worsening of visual acuity on right eye 6 months after the treatment.


At the first visit the patient presented a corrected visual acuity of OD 0.4 OI 0.7 (LogMAR). No corneal ectasia was demonstrated on topography. Biomicroscopy showed diffused stromal opacification and central scars on the left eye and dentritic ulcer on the right eye. Treatment with topical and oral antivirus was performed and ocasional therapeutic contact lens, with a slow evolution and resolution after fifteen months of follow up. Currently the corrected distance visual acuity improved to 0.6 on the right eye. The case was illustrated using the slit lamp and anterior segment OCT Cirrus-Hd 4000.


Primary herpes simplex keratitis can occurs after cross-linking in patients with herpes disease on the contralateral eye and that condition may be consider a contraindication of that treatment.

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