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Phototherapeutic keratectomy versus manual epithelial debridement for corneal collagen cross-linking: 1 year outcomes of 281 eyes with progressive corneal ectasia

Poster Details

First Author: P.Arjmand CANADA

Co Author(s):    J. Teichman   D. Kurowecki   R. Conlan    S. Ziai    G. Mintsioulis   B. Jackson   K. Baig  

Abstract Details


To evaluate and compare the long-term effectiveness of mechanical epithelial debridement using a manual brush versus transepithelial phototherapeutic keratectomy (PTK) combined with corneal collagen cross-linking (CXL) in eyes with progressive corneal ectasia


Ottawa Eye Institute,The Ottawa Hospital, Ottawa, Ontario.


Retrospective review of 330 eyes with progressive corneal ectasia undergoing CXL combined with either mechanical epithelial debridement (“brush”) (n = 258) or PTK (n = 72 eyes).


There was a significant improvement in all refractive and topographic outcomes (i.e. UDVA, BCVA, sphere, cylinder, K mean, K flat, K steep, K max and pachymetry values) in all CXL eyes at 12 months (p<0.005). There was a significant improvement in UDVA with eyes treated with PTK-CXL versus brush at 12 months. There was no difference in other refractive (CDVA, sphere, cylinder) or topographic outcomes (i.e. K mean, K flat, K steep, K max) between the two groups.


Corneal collagen cross-linking significantly improves all refractive and topographic data with either PTK or manual epithelial debridement at 12 months post-operatively. Both techniques are comparable in refractive and topographic outcomes, except for UDVA, which was better in the PTK group compared to the brush group.

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