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Topography-guided photorefractive keratectomy with simultaneous cross-linking in patients with early and moderate keratoconus

Poster Details

First Author: F.Abdulaliyeva AZERBAIJAN

Co Author(s):    T. Huseynova                    

Abstract Details


To evaluate the clinical outcomes after simultaneous topography-guided photorefractive keratectomy (PRK) and crosslinking (CXL) in patients with early and moderate keratoconus.


National Ophthalmology Center named after Z.Aliyeva, Baku, Azerbaijan.


Twenty patients (30 eyes) with early and moderate keratoconus were included in the study. All patients underwent customized topography-guided PRK which was immediately followed by the CXL procedure. The epithelium was removed by transepithelial phototherapeutic keratectomy in all cases. Uncorrected distance visual acuity (UDVA), manifest refraction spherical equivalent (MRSE), endothelial cell density (ECD), and also parameters from Pentacam topography (Oculus, Wetzlar, Germany) were evaluated pre- and postoperatively. The follow up period was 24 months.


There was a significant difference in UDVA, MRSE, and keratometry values (p<0.05 for all) postoperatively. The parameters of corneal variance indices, such as Index of Surface Variance (ISV), Index of Vertical Asymmetry (IVA), Center keratoconus Index (CKI), Index of Height Asymmetry (IHA) and Index of Height Decentration (IHD), radius minimum (RM) from Pentacam, were also changed significantly (p<0.05 for all).


Simultaneous PRK and CXL are considered as an alternative treatment in our series of early and moderate keratoconic patients.

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