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Combined topical application of a regenerative agent with a bandage contact lens for the treatment of persistent epithelial defects

Poster Details

First Author: D.Liakopoulos GREECE

Co Author(s):    G. Kymionis   M. Grentzelos   V. Diakonis   K. Tsoulnaras   M. Tsilimbaris   I. Pallikaris     

Abstract Details


The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a bandage contact lens (BCL).


Vardinoyiannion Eye Institute of Crete (VEIC), Faculty of Medicine, University of Crete, Heraklion, Crete, Greece


Three patients suffering from a PED for 4–8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL.


The PED healed in all patients after 4–21 days, and no side effects were noted. No recurrence observed during the follow-up period.


The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.

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