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Single intracameral injection of Triamcinolone Acetonide for paediatric cataract surgery

Poster Details

First Author: K.Solaiman EGYPT

Co Author(s):    E. Maaly   H. Al Bialy   R. Dessouky              

Abstract Details

Purpose:

To evaluate the safety and efficacy of a single intracameral injection of Triamcinolone Acetonide in controlling postoperative ocular inflammation and improving the outcome of pediatric cataract surgery with intraocular lens implantation.

Setting:

Ophthalmology department, Zagazig University Hospital; the main tertiary hospital in Sharkeya governerate, Egypt.

Methods:

Quasi study in which Patients were divided into two almost equal age and sex matched groups. The study group included eyes that received intracameral injection of 4 mg/0.13 ml of preservative-free Triamcinolone Acetonide at the end of surgery while the control group included eyes that did not receive intracameral injection of Triamcinolone Acetonide. Postoperative examinations were done on day 1 then weekly for 1 month, and monthly for another 2 months. Primary outcome measures included any sign of anterior segment inflammation, while secondary outcome measures included best corrected visual acuity, intraocular pressure and any reported complication from the drug.

Results:

The study included 42 eyes (35 patients):21 eyes in each group. Postoperative inflammatory membrane was statistically significant higher in the control group than in the study group (P=0.018). The mean duration of using topical steroids in the study group (17.2±4.1 days) was statistically significant less than its mean duration (28.3±3.4 days) in the control group (P<0.05). No statistically significant differences were detected between preoperative and postoperative intraocular pressure in each group and in between both groups. No significant complications related to intracameral triamcinolone acetonide were reported.

Conclusions:

A single intracameral injection of 4 mg preservative free triamcinolone acetonide at the end of uncomplicated pediatric cataract surgery could be an effective and safe adjunct to postoperative topical steroids in controlling postoperative ocular inflammation.

Financial Disclosure:

NONE

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