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Adhesion property between ophthalmic viscosurgical devices and intraocular lenses

Poster Details

First Author: T.Uda JAPAN

Co Author(s):    T. Suzuki   Y. Ohashi                 

Abstract Details

Purpose:

A common complication of ophthalmic viscosurgical devices (OVDs) after cataract surgery is an increase in postoperative intraocular pressure (IOP). Moreover OVDs contaminated with bacteria in the lens capsule during cataract surgery could induce postoperative endophthalmitis. To reduce the risk of IOP spike and endophthalmitis, it is important to remove potentially contaminated OVDs from the intraocular lens (IOL). The efficiency of removal could relate to the adhesive properties between the OVD and the IOL. This study was conducted to examine the adhesive property to facilitate the understanding how various IOLs might interact with various OVDs.

Setting:

Department of Ophthalmology, Ehime university, Graduate School of Medicine

Methods:

Three commercially available IOLs (A: Eternity uni W-60, Santen, Japan; B: iSert 251, HOYA, Japan; C: Acrysof-SA60AT, Alcon, U.S.A.), and three OVDs (D: Opegan-hi, Santen, Japan; E: Healon, Abbot, U.S.A.; F, DisCoVisc, Alcon, U.S.A.) were studied. D and E are cohesive OVDs, and F provides both cohesive and dispersive properties .Three IOLs were set on the center of a plastic chamber, and 0.05 ml of each OVD was placed on the center of IOL. The chamber was filled with water and water flow was created. We measured the time of completely OVD detachments from the IOL.

Results:

The mean times of OVDs (D and E) detachments from each IOL (A, B, or C) were as follows: D (A; 88±41, B; 113±13, C; 101±25 seconds) and E: (A; 56±25, B; 90±14, C; 72±23 seconds) (N=3). The mean times of cohesive OVDs detachments were not significantly different among IOLs. The all mean time of OVD-F detachments from each IOL (A, B, or C) were longer than 180 seconds. OVD-F had been reminded for significantly longer time on all tested IOLs, compared with cohesive OVDs (A and B) (P<0.05).

Conclusions:

Adhesion property between cohesive OVDs and IOL are similar, and may not be depends on kinds of IOL. It could be easy to remove cohesive OVDs from IOL. In contrast, the cohesive and dispersive OVD may attach rigidly to surface of IOLs. For prevention of IOP spike and endophthalmitis, we may need longer time to remove the cohesive and dispersive OVD.

Financial Disclosure:

One or more of the authors gains financially from competing product or procedure, One or more of the authors research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One or more of the authors gains financially from product or procedure presented

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