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Effect on intraocular pressure and endothelial cell count after phacoemulsification with 3 different classes of ophthalmic viscoelastic devices: a prospective randomized controlled study

Poster Details

First Author: Z.Pulpattil Areakat SAUDI ARABIA

Co Author(s):    M. Yasmin                    

Abstract Details

Purpose:

To compare effect of three OVDs DisCoVisc, Microvisc, Visthesia on intraocular pressure and endothelial cell count following phacoemulsification.

Setting:

Department of Ophthalmology, Dr. Sulaiman al Habib Medical group, Riyadh, Saudi Arabia

Methods:

This randomized prospective clinical study conducted in 44 eyes of 37 patients. All eyes were undergone phacoemulsification by same surgeon. One of the 3 OVDs were used for all steps of surgery. Sodium hyaluronate 1%( Microvisc), Sodium hyaluronate 1.6% and Sodium chondroitin sulphate 4% (DisCoVisc), Sodium hyaluronate1.5% and lidocaine hydrochloride 1%(Visthesia). Exclusion criteria includes age above 75, endothelial dystrophy, history of uveitis, previous intraocular surgery, preoperative IOP above 21. IOP was measured by Goldmann applanation tonometry preoperative, 6hour, 24 hour, 1 week and 1 month post surgery. ECD were measured pre and 1 month post operation using Tomey EM3000.

Results:

All 3 groups had increased IOP 6 hour postsurgery. The highest mean IOP was 27mmHg in DisCoVisc group, which persisted in 1stday followup and stabilized in further visits.Mean IOP rise in other 2 groups were minimal 23.8mmHg(Visthesia) and 23.1(Microvisc). Corneal edema was highest in DisCoVisc group which stabilized in 1 week visits, whereas in other 2 groups corneal edema was minimal or absent in 1st postoperative day. Mean Endothelial cell count loss were 9.6% at 1 month followup. The difference between OVD groups were not statistically significant.

Conclusions:

All 3 different classes of OVD had immediate intraocular pressure rise with highest in DisCoVisc group which stabilised in 1week followup. Endothelial cell loss were comparable in all 3 groups. Corneal edema associated with DisCoVisc group related to raised IOP and endothelial pumping disturbances in the first week.

Financial Disclosure:

NONE

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