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Comparison of three designs of PCO-preventing rings

Poster Details

First Author: G.Kleinmann ISRAEL

Co Author(s):    L. Slutzky                    

Abstract Details

Purpose:

To investigate three designs of open capsule ring (OCR) with different size and density of side wall apertures on PCO and Sommering's ring formation

Setting:

Ophthalmology Department, Kaplan Medical Center and Harlan Biotec, Israel

Methods:

24 NZW rabbits' eyes were divided into 3 groups. 3 different OCRs were implanted into the capsular bag after crystalline lens evacuation. Group A (n=8): 190 degrees of large side wall apertures, group B (n=9): 90 degrees of small side wall apertures, and group C (n=7): 175 degrees of small side wall apertures. The same intraocular lens was then implanted into the OCR. A weekly slit lamp exam was performed for the 6 weeks of the study duration. After 6 weeks the rabbits were scarified, the eyes were enucleated and fixated and then evaluated using the Miyake-Apple view and histology.

Results:

Similar low PCO levels and Sommering's ring formation were found in all the study groups. Six weeks slit lamp PCO level were: A: 0.4±0.7, B: 0.8±0.8, C: 0.4±0.8; p=0.5. Histology PCO level were: A: 0±0, B: 0.7±0.1, C: 0.4±1.1; p=0.25, Sommering's Ring area(%): A: 24+14, B: 23+12, C: 20+14; p=0.38. Area of Sommering's ring protrusion inside the OCR (%): A: 12+10, B:10+9, C: 9+9, P=0.31.

Conclusions:

The three OCR designs showed similar PCO and Sommering's ring prevention. There was no difference in the Sommering's ring protrusion inside the different OCRs.

Financial Disclosure:

One or more of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, One or more of the authors research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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