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Relationship of quantum of energy used and loss of corneal endothelial cell density following Nd:YAG laser capsulotomy for posterior capsular opacification

Poster Details

First Author: H.Chawla INDIA

Co Author(s):    M. Singh   S. Vashisht   K. Jain              

Abstract Details


Aim of this study was to evaluate change in corneal endothelial cell density (CD) following Neodymium: Yttrium Aluminum Garnet (Nd:YAG) capsulotomy among patients with posterior capsular opacification (PCO).


Department of Ophthalmology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India


A prospective observational study was conducted on 181 eyes that underwent Nd:YAG posterior capsulotomy. One hundred and fifty six patients completed the study. Patients were grouped, depending on quantum of energy used, into Group A (≤ 40 mJ), B (40 - 80 mJ) and C (> 80 mJ). Corneal endothelial density was recorded prior to laser, at one week and one month post laser.


Average duration since surgery was 2.45 years. Average total energy used was 56.23 mJ. Mean fall in CD from baseline at 1 week was 0.3 ± 0.35% in Group A (p= 0.196), 0.4 ± 3.6% in Group B (p= 0.043) and 1.5 ± 5.4% in Group C (p = 0.001). At 1 month, fall in CD was 0.4 ± 0.9% (p=0.761), 0.5 ± 6% (p=0.005) and 2.0 ± 5.6% (p= < 0.001) respectively. Thus fall in CD was observed only in groups that received > 40 mJ of energy and was higher with use of higher amount of energy.


Loss of endothelial cells is proportional to quantum of energy used to achieve optimum Nd:YAG laser capsulotomy and does not change significantly over a period of one month.

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