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New experimental design of phakic intraocular lens for presbyopia correction

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Session Details

Session Title: Presented Poster Session: Phakic IOLs

Session Date/Time: Monday 07/09/2015 | 09:30-10:50

Paper Time: 09:40

Venue: Poster Village: Pod 2

First Author: : C.Perez-Vives SPAIN

Co Author(s): :    T. Ferrer-Blasco   A. Cervino   D. Madrid-Costa   R. Montes-Mico     

Abstract Details


To evaluate the visual impact of adding different spherical aberration (SA) values to an Implantable Collamer Lens (ICL) to increase the depth of focus (DoF) using an adaptive optics visual simulator.


Valencia University Clinic, Spain.


Wavefront aberrations of the -3 and -6 diopters (D) ICLs were measured in vitro at 3- and 4.5-mm pupil. Afterwards, different simulated ICL experimental prototypes were created, varying the SA. An adaptive optics visual simulator was programmed to measure and compensate for a particular eye's wavefront error and simulate vision after the implantation of the different ICL prototypes from their wavefront aberrations plus the average ocular HOAs. Best-corrected distance visual acuity (BDVA) and DoF were measured with the accommodation paralyzed in 10 eyes of 10 subjects at 3- and 4.5-mm pupils.


At 3-mm pupil, the BDVA achieved with -3.00 and -6.00D ICLs and all ICL prototypes evaluated was high, above 20/20; except for -6D ICL + SA4 at 50% BDVA contrast which decreased to 20/25. However, at 4.5-mm pupil, BDVA obtained with the ICL prototypes decreased significantly, being more pronounced when the SA induced was negative. The DoF increase was statistically significant with the highest SA values added to the ICL prototypes. The DoF increment was larger with the highest SA added and with small pupil. Nevertheless, it was independent of the sign of the added SA.


The outcomes of the present study show that a residual of negative SA after ICL implantation will disrupt the BDVA. However, certain residual of positive SA after ICL implantation increases the DoF, achieving a growth from up to 60%, with excellent BDVA values, then, providing a possible ICL design for young-presbyopic patients.

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