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The effect of dehydration and religious fasting on corneal biomechanical properties and intraocular pressure

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Session Details

Session Title: Presented Poster Session: Corneal Biomechanics

Session Date/Time: Sunday 06/09/2015 | 09:30-11:00

Paper Time: 09:30

Venue: Poster Village: Pod 4

First Author: : R.Oltulu TURKEY

Co Author(s): :    R. Oltulu   G. Satirtav   I. Ersan   E. Soylu   M. Okka   N. Zengin

Abstract Details


To evaluate the changes in corneal biomechanical properties and intraocular pressure (IOP) during fasting period in healthy subjects.


Necmettin Erbakan University, Meram Faculty of Medicine, Ophthalmology Department


Seventy-two eyes of 72 fasting subjects (study group), and 62 eyes of 62 non-fasting subjects (control group) were enrolled in this prospective study undertaken at a single university hospital. All subjects underwent complete ophthalmologic examination, including ocular biomechanical evaluation with ocular response analyzer (ORA). The corneal hysteresis (CH), corneal resistance factor (CRF), mean corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) values were measured with a patented dynamic bidirectional applanation process.


IOPg and IOPcc measurements in the study group and the control group were found as 13.8±2.8 mmHg, 14.6±2.6 mmHg and 16.3±2.2 mmHg, 15.7±2.4 mmHg respectively. There was statistically significant difference within the two groups in IOPg and IOPcc (p<0.001). In addition to CH and CRF significantly decreased in study group compared to control group (p<0.001, p=0.012, respectively)


Prolonged fasting causes a significant decrease in IOPg, IOPcc, CH and CRF in healthy subjects, altering the biomechanical properties of the cornea.

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